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Related Experiment Videos

The artificial heart - progress, problems, and further development

E S Bücherl

    Medical Progress Through Technology
    |July 20, 1976
    PubMed
    Summary
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    This research reviews artificial heart development, focusing on biomaterials, pump design, and energy transmission. It highlights challenges in hemodynamics and proposes new regulation methods for implantable artificial hearts.

    Area of Science:

    • Biomedical Engineering
    • Cardiovascular Research
    • Artificial Organs

    Background:

    • Current artificial heart research is advancing, informed by extensive animal experimentation and collaborative efforts.
    • Key challenges include ensuring biomaterial compatibility, optimizing pump hydrodynamics to prevent clotting, and developing efficient energy transmission systems.

    Purpose of the Study:

    • To provide a comprehensive overview of the state-of-the-art in artificial heart development.
    • To address critical issues such as biomaterial selection, pump design, energy supply, and physiological regulation.
    • To explore future directions for totally implantable artificial heart systems.

    Main Methods:

    • Review of over 100 animal experiments and existing research.
    • Analysis of biomaterial properties (blood compatibility, mechanical strength, durability).

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  • Hemodynamic measurements in systemic and pulmonary circulation, evaluation of pump regulation, and assessment of pathophysiological effects.

    • Main Results:

    • Identified difficulties in venous inflow and pump regulation.
    • Demonstrated the impact of an active artificial atrium and novel computerized regulation strategies.
    • Detailed pathophysiological findings in multiple organ systems (lung, kidney, GI tract, blood).

    Conclusions:

    • Significant progress has been made in artificial heart technology, addressing key challenges in materials, hydrodynamics, and energy systems.
    • Advanced regulation techniques and active artificial atria show promise for improved function.
    • Miniaturization and new energy supply methods are crucial for future totally implantable artificial heart systems.