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Non-secretory solitary plasmacytoma of the spleen
M D Colović1, G M Janković, R B Colović
1Institute of Hematology, Clinical Center of Serbia, Belgrade, Yugoslavia.
Medical Oncology (Northwood, London, England)
|February 10, 1999
Abstract:
A case of primary nonsecretory plasmacytoma of the spleen is reported. On laparotomy and splenectomy a 920 g spleen was removed, measuring 16 x 14 x 6 cm. The cut surface of the entire spleen showed that the tumour occupied most of the splenic tissue. A bone marrow aspirate and trephine, skeletal survey showed no signs of myeloma. Biopsy of the liver and regional lymph nodes was normal. Immunocytochemistry of the splenic tumour showed positivity for pan-B and plasma cell markers. After splenectomy the patient was treated with chemotherapy according to protocol VBCMP (M2).