Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Problem Solving: Volume01:13

Problem Solving: Volume

80
The volume of a fuel tank mounted on the wing of a jet aircraft can be modeled using the concept of solids of revolution. In this case, the tank is formed by rotating a two-dimensional region, defined by a mathematical function, about the x-axis. The region extends along the axis from zero to two meters, and the resulting three-dimensional shape is symmetric about the axis of rotation. Because the boundary curve lies directly against the axis, the disk method is an appropriate technique for...
80
Lung Capacity01:47

Lung Capacity

56.4K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.4K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

75.8K
Oxidation–Reduction Reactions
75.8K
Constant Volume Calorimetry02:41

Constant Volume Calorimetry

30.8K
Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...
30.8K
Volume of Distribution01:20

Volume of Distribution

1.3K
The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.
1.3K
Respiratory Volumes01:15

Respiratory Volumes

3.0K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

Physical review letters·2022
Same author

[Differential Diagnosis of Pulmonary Hypertension Using the Example of Collagenosis-associated PAH in the Context of Chronic Lung and Left Heart Disease].

Pneumologie (Stuttgart, Germany)·2021
Same author

[Current Aspects of Definition and Diagnosis of Pulmonary Hypertension].

Pneumologie (Stuttgart, Germany)·2020
Same author

[Current Aspects of Definition and Diagnosis of Pulmonary Hypertension].

Pneumologie (Stuttgart, Germany)·2020
Same author

[Expert Workshop COPD: Lungs and Heart - Quite Often Ill Together].

Pneumologie (Stuttgart, Germany)·2019
Same journal

Pelvic venous disease and lymphatic dysfunction: evaluating the evidence for a proposed continuum.

The Journal of cardiovascular surgery·2026
Same journal

Incidence of post-dissection aneurysmal formation and need for secondary intervention after surgery for acute type A aortic dissections: a systematic review and meta-analysis of observational studies.

The Journal of cardiovascular surgery·2026
Same journal

The expertise effect: how advancing skills in frozen elephant trunk have broadened surgical indication for acute dissection.

The Journal of cardiovascular surgery·2026
Same journal

Outcomes of pulmonary embolism response teams: a systematic review.

The Journal of cardiovascular surgery·2026
Same journal

Use of large bore devices in the treatment of pulmonary embolism.

The Journal of cardiovascular surgery·2026
Same journal

Contemporary role of systemic thrombolysis in the management of acute pulmonary embolism.

The Journal of cardiovascular surgery·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
05:48

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice

Published on: September 26, 2019

9.9K

Lung volume reduction surgery for severe emphysema

S Demertzis1, H Wilkens, M Lindenmeir

  • 1Department of Thoracic & Cardiovascular Surgery, University Hospital Homburg/Saar, Saarland University, Germany.

The Journal of Cardiovascular Surgery
|February 11, 1999
PubMed
Summary
This summary is machine-generated.

Lung volume reduction surgery (LVRS) significantly improves breathing and mobility for advanced emphysema patients. This effective treatment offers a promising alternative for selected individuals, potentially serving as a bridge to lung transplantation.

More Related Videos

Measurement of the Pressure-volume Curve in Mouse Lungs
09:49

Measurement of the Pressure-volume Curve in Mouse Lungs

Published on: January 27, 2015

19.4K
Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice
10:37

Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice

Published on: January 16, 2015

13.7K

Related Experiment Videos

Last Updated: Feb 8, 2026

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
05:48

Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice

Published on: September 26, 2019

9.9K
Measurement of the Pressure-volume Curve in Mouse Lungs
09:49

Measurement of the Pressure-volume Curve in Mouse Lungs

Published on: January 27, 2015

19.4K
Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice
10:37

Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice

Published on: January 16, 2015

13.7K

Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Respiratory Medicine

Background:

  • Advanced emphysema causes severe dyspnea, significantly impacting patient quality of life.
  • Lung volume reduction surgery (LVRS) is a surgical option for severe emphysema.
  • Optimal patient selection is crucial for successful LVRS outcomes.

Purpose of the Study:

  • To evaluate the mid-term outcomes of 25 consecutive lung volume reduction operations (LVRS).
  • To assess the efficacy of LVRS in improving dyspnea, mobility, and pulmonary function in patients with advanced emphysema.

Main Methods:

  • Prospective study of 25 patients undergoing LVRS, followed for 12 months post-surgery.
  • Patient selection criteria included severe dyspnea, airway obstruction, lung overinflation, and completed rehabilitation, excluding severe hypercarbia.
  • Surgical interventions involved bilateral LVRS in 22 patients and unilateral LVRS in 3 patients.

Main Results:

  • Significant improvements observed in dyspnea (MRC score) and 6-minute walking distance at 12 months post-LVRS.
  • Pulmonary function tests showed significant improvements in airway obstruction (FEV1) and lung overinflation (TLC, RV).
  • LVRS outcomes were superior to those of conservatively treated patients.

Conclusions:

  • Lung volume reduction surgery (LVRS) is an effective treatment for selected patients with end-stage emphysema.
  • LVRS offers significant improvements in respiratory function and quality of life.
  • LVRS can be considered a viable alternative or a bridge to lung transplantation.