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[Limitations of and criteria for a coronary thrombosis model]
Zeitschrift Fur Experimentelle Chirurgie
|October 1, 1976
Insights
New therapeutic strategies for coronary thrombosis are needed due to rising cardiac infarction rates. This study reviews current coronary thrombosis models and their limitations, outlining criteria for reliable patterns.
Area of Science:
- Cardiovascular Science
- Thrombosis Research
Context:
- Increasing incidence of cardiac infarction.
- Strong correlation between cardiac infarction and coronary thrombosis.
- Need for novel therapeutic interventions for coronary thrombosis.
Purpose:
- To review existing principles of coronary thrombosis models.
- To identify the limitations of current models.
- To define criteria for a reliable coronary thrombosis pattern.
Summary:
- Discusses the principles of established coronary thrombosis models.
- Highlights the limitations and reliability issues of current models.
- Presents essential criteria for developing effective coronary thrombosis patterns.
Impact:
- Facilitates the development of more accurate preclinical models for coronary thrombosis.
- Aids in the evaluation and selection of appropriate models for therapeutic research.
- Contributes to advancing the understanding and treatment of coronary thrombosis and cardiac infarction.
Abstract:
The increasing frequency of cardiac infarction and its close correlation with coronary thrombosis urge to seek for new therapeutic approaches to coronary thrombosis. Proper models are necessary for that. The principles hitherto published are reported as well as the limits of their reliability, and the demanded criteria of a pattern of coronary thrombosis are demonstrated.