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Nature Communications|July 2, 2021
High-resolution characterization of gene function using single-cell CRISPR tiling screenLu Yang, Anthony K N Chan, Kazuya Miyashita, et al.
Blood|December 14, 2023
Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AMLWallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, et al.
Science Advances|February 23, 2024
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug DiscoveryAnthony K N Chan, Li Han, Christopher D Delaney, et al.
Nature Cancer|May 9, 2022
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemiaBrandon J Aubrey, Jevon A Cutler, Wallace Bourgeois, et al.
Molecular Cancer|December 4, 2023
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemiaNuria Tubío-Santamaría, Ashok Kumar Jayavelu, Tina M Schnoeder, et al.
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