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Journal of Immunology (Baltimore, Md. : 1950)|November 21, 2001
Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor moleculeA Hombach, A Wieczarkowiecz, T Marquardt, et al.
Anticancer Research|May 1, 1997
Activation of resting T cells against the CA 72-4 tumor antigen with an anti-CD3/CA 72-4 bispecific antibody in combination with a costimulatory anti-CD28 antibodyA Hombach, S Mathas, M Jensen, et al.
Clinical and Experimental Immunology|May 1, 1997
Specific activation of resting T cells against tumour cells by bispecific antibodies and CD28-mediated costimulation is accompanied by Th1 differentiation and recruitment of MHC-independent cytotoxicityA Hombach, T Tillmann, M Jensen, et al.
International Journal of Molecular Medicine|December 17, 1998
Chimeric anti-TAG72 receptors with immunoglobulin constant Fc domains and gamma or zeta signalling chainsA Hombach, R Sircar, C Heuser, et al.
Gastroenterology|July 4, 2012
T cells that target carcinoembryonic antigen eradicate orthotopic pancreatic carcinomas without inducing autoimmune colitis in miceMarkus Chmielewski, Olga Hahn, Gunter Rappl, et al.
Plos One|April 28, 2012
A proteomic view at T cell costimulationRudolf Lichtenfels, Gunter Rappl, Andreas A Hombach, et al.
Gene Therapy|June 26, 2001
T cells engrafted with a recombinant anti-CD30 receptor target autologous CD30(+) cutaneous lymphoma cellsA Hombach, J M Muche, M Gerken, et al.
International Journal of Cancer|November 11, 1993
A CD16/CD30 bispecific monoclonal antibody induces lysis of Hodgkin's cells by unstimulated natural killer cells in vitro and in vivoA Hombach, W Jung, C Pohl, et al.
Gut|September 29, 2005
A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3zeta-CD28 signalling targets T cells from colorectal cancer patients against their tumour cellsA Hombach, C Schlimper, E Sievers, et al.
The Journal of Investigative Dermatology|May 8, 1999
Specific lysis of melanoma cells by receptor grafted T cells is enhanced by anti-idiotypic monoclonal antibodies directed to the scFv domain of the receptorU Reinhold, L Liu, H C Lüdtke-Handjery, et al.
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