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The Biochemical Journal|April 28, 2023
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinaseCatia L Pierotti, Annette V Jacobsen, Christoph Grohmann, et al.Vaccine|June 10, 2011
Inactivated polio vaccine development for technology transfer using attenuated Sabin poliovirus strains to shift from Salk-IPV to Sabin-IPVWilfried A M Bakker, Yvonne E Thomassen, Aart G van't Oever, et al.Journal of Medicinal Chemistry|March 4, 2011
Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activityBrad E Sleebs, Peter E Czabotar, Wayne J Fairbrother, et al.Mucosal Immunology|February 8, 2018
Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccinationR H M Raeven, J Brummelman, J L A Pennings, et al.Nature Communications|June 23, 2018
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosisEmma J Petrie, Jarrod J Sandow, Annette V Jacobsen, et al.Cell Reports|September 26, 2019
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3Emma J Petrie, Jarrod J Sandow, Wil I L Lehmann, et al.Nature Chemical Biology|April 23, 2013
Structure-guided design of a selective BCL-X(L) inhibitorGuillaume Lessene, Peter E Czabotar, Brad E Sleebs, et al.Journal of Medicinal Chemistry|June 18, 2013
Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XLBrad E Sleebs, Wilhemus J A Kersten, Sanji Kulasegaram, et al.ACS Chemical Biology|September 9, 2020
Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the PathwayCatia L Pierotti, Maria C Tanzer, Annette V Jacobsen, et al.ACS Medicinal Chemistry Letters|June 20, 2014
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XLMichael F T Koehler, Philippe Bergeron, Edna F Choo, et al.Pageof 12