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Journal of Medicinal Chemistry
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December 22, 2023
Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors
Kristopher W Hoyt, Daniel A Urul, Blessing C Ogboo, et al.
Journal of Chemical Information and Modeling
|
June 17, 2023
Targeting SARS-CoV-2 Main Protease (MPro) with Kinase Inhibitors: A Promising Approach for Discovering Antiviral and Anti-inflammatory Molecules against SARS-CoV-2
Débora Bublitz Anton, Júlia Galvez Bulhões Pedreira, Maria Luiza Zvirtes, et al.
Nature Chemical Biology
|
December 27, 2011
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
Solveigh C Koeberle, Johannes Romir, Stefan Fischer, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 20, 2024
Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in <i>KRAS</i>-mutant cancers
Robin A Jansen, Sara Mainardi, Matheus Henrique Dias, et al.
Journal of Medicinal Chemistry
|
June 1, 2018
Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold
Michael Forster, Apirat Chaikuad, Teodor Dimitrov, et al.
Journal of Medicinal Chemistry
|
December 6, 2014
Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases
Felix Muth, Marcel Günther, Silke M Bauer, et al.
Journal of Medicinal Chemistry
|
April 11, 2024
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S<sub>N</sub>Ar Electrophiles
Moritz Schwarz, Maksym Kurkunov, Florian Wittlinger, et al.
Cell Chemical Biology
|
November 15, 2016
Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket
Michael Forster, Apirat Chaikuad, Silke M Bauer, et al.
Journal of Medicinal Chemistry
|
December 16, 2016
Tri- and Tetrasubstituted Pyridinylimidazoles as Covalent Inhibitors of c-Jun N-Terminal Kinase 3
Felix Muth, Ahmed El-Gokha, Francesco Ansideri, et al.
Journal of Medicinal Chemistry
|
February 27, 2015
Correction to Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases
Felix Muth, Marcel Günther, Silke M Bauer, et al.
Page
of 19
Search research articles
Search
Showing results (141-150 of 189) with videos related to
Sort By:
Page
of 19
Journal of Medicinal Chemistry
|
December 22, 2023
Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors
Kristopher W Hoyt, Daniel A Urul, Blessing C Ogboo, et al.
Journal of Chemical Information and Modeling
|
June 17, 2023
Targeting SARS-CoV-2 Main Protease (MPro) with Kinase Inhibitors: A Promising Approach for Discovering Antiviral and Anti-inflammatory Molecules against SARS-CoV-2
Débora Bublitz Anton, Júlia Galvez Bulhões Pedreira, Maria Luiza Zvirtes, et al.
Nature Chemical Biology
|
December 27, 2011
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
Solveigh C Koeberle, Johannes Romir, Stefan Fischer, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 20, 2024
Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in <i>KRAS</i>-mutant cancers
Robin A Jansen, Sara Mainardi, Matheus Henrique Dias, et al.
Journal of Medicinal Chemistry
|
June 1, 2018
Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold
Michael Forster, Apirat Chaikuad, Teodor Dimitrov, et al.
Journal of Medicinal Chemistry
|
December 6, 2014
Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases
Felix Muth, Marcel Günther, Silke M Bauer, et al.
Journal of Medicinal Chemistry
|
April 11, 2024
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S<sub>N</sub>Ar Electrophiles
Moritz Schwarz, Maksym Kurkunov, Florian Wittlinger, et al.
Cell Chemical Biology
|
November 15, 2016
Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket
Michael Forster, Apirat Chaikuad, Silke M Bauer, et al.
Journal of Medicinal Chemistry
|
December 16, 2016
Tri- and Tetrasubstituted Pyridinylimidazoles as Covalent Inhibitors of c-Jun N-Terminal Kinase 3
Felix Muth, Ahmed El-Gokha, Francesco Ansideri, et al.
Journal of Medicinal Chemistry
|
February 27, 2015
Correction to Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases
Felix Muth, Marcel Günther, Silke M Bauer, et al.
Page
of 19