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Journal of Medicinal Chemistry|May 6, 2016
Effects of N-Substitutions on the Tetrahydroquinoline (THQ) Core of Mixed-Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) LigandsAubrie A Harland, Aaron M Bender, Nicholas W Griggs, et al.Journal of Medicinal Chemistry|March 28, 2019
Dual Pharmacophores Explored via Structure-Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand DesignAnthony F Nastase, Jessica P Anand, Aaron M Bender, et al.Bioorganic & Medicinal Chemistry Letters|April 22, 2017
Synthesis and evaluation of 4,6-disubstituted pyrimidines as CNS penetrant pan-muscarinic antagonists with a novel chemotypeAaron M Bender, Rebecca L Weiner, Vincent B Luscombe, et al.Journal of Natural Products|April 1, 2025
Total Synthesis and Pharmacological Evaluation of Phochrodines A-CJacob L Bouchard, Sichen Chang, Srinivasan Krishnan, et al.ACS Medicinal Chemistry Letters|February 14, 2024
Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 AgonistsNavoda Jayakodiarachchi, Mallory A Maurer, Daniel C Schultz, et al.Cancer Research|April 15, 2010
Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomasAaron M Bender, Lara S Collier, Fausto J Rodriguez, et al.Bioorganic & Medicinal Chemistry Letters|June 12, 2021
Discovery of a novel class of heteroaryl-pyrrolidinones as positive allosteric modulators of the muscarinic acetylcholine receptor M1Paul K Spearing, Hyekyung P Cho, Vincent B Luscombe, et al.Molecular Pharmacology|August 18, 2023
Development of a Selective and High Affinity Radioligand, [3H]VU6013720, for the M4 Muscarinic ReceptorAidong Qi, Haley E Kling, Natasha Billard, et al.Biorxiv : the Preprint Server for Biology|February 20, 2025
Cryo-EM reveals a new allosteric binding site at the M5 mAChRWessel A C Burger, Jesse I Mobbs, Bhavika Rana, et al.Nature Communications|July 31, 2025
Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChRWessel A C Burger, Jesse I Mobbs, Bhavika Rana, et al.Pageof 5