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ACS Chemical Biology
|
July 23, 2019
CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins
Aarti Kawatkar, Michelle Schefter, Nils-Olov Hermansson, et al.
ACS Chemical Biology
|
March 21, 2024
Integrated Proteomics Characterization of NLRP3 Inflammasome Inhibitor MCC950 in Monocytic Cell Line Confirms Direct MCC950 Engagement with Endogenous NLRP3
Heng Zhao, Praveen Kumar, Tiago Jose Paschoal Sobreira, et al.
ACS Chemical Biology
|
January 5, 2023
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, et al.
Journal of Medicinal Chemistry
|
December 16, 2022
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology
Frederick W Goldberg, Jason G Kettle, Gillian M Lamont, et al.
Chemmedchem
|
April 4, 2017
Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2
Matias Casás-Selves, Andrew X Zhang, James E Dowling, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 29, 2015
Identification of azabenzimidazoles as potent JAK1 selective inhibitors
Melissa M Vasbinder, Marat Alimzhanov, Martin Augustin, et al.
Journal of Medicinal Chemistry
|
June 2, 2018
Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors
Neil P Grimster, Erica Anderson, Marat Alimzhanov, et al.
Cell Reports. Medicine
|
March 8, 2023
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice
Rebecca Jarvis, Shu Fun Josephine Ng, Anna J Nathanson, et al.
Journal of Medicinal Chemistry
|
December 23, 2025
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular Tool
J Henry Blackwell, Simon C C Lucas, Giovanni Battocchio, et al.
ACS Chemical Biology
|
October 19, 2018
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6
William McCoull, Tony Cheung, Erica Anderson, et al.
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of 1
Search research articles
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Showing results (1-10 of 10) with videos related to
Sort By:
Page
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ACS Chemical Biology
|
July 23, 2019
CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins
Aarti Kawatkar, Michelle Schefter, Nils-Olov Hermansson, et al.
ACS Chemical Biology
|
March 21, 2024
Integrated Proteomics Characterization of NLRP3 Inflammasome Inhibitor MCC950 in Monocytic Cell Line Confirms Direct MCC950 Engagement with Endogenous NLRP3
Heng Zhao, Praveen Kumar, Tiago Jose Paschoal Sobreira, et al.
ACS Chemical Biology
|
January 5, 2023
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit
Aarti Kawatkar, Roger A Clark, Lorna Hopcroft, et al.
Journal of Medicinal Chemistry
|
December 16, 2022
Discovery of Clinical Candidate AZD0095, a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology
Frederick W Goldberg, Jason G Kettle, Gillian M Lamont, et al.
Chemmedchem
|
April 4, 2017
Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2
Matias Casás-Selves, Andrew X Zhang, James E Dowling, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 29, 2015
Identification of azabenzimidazoles as potent JAK1 selective inhibitors
Melissa M Vasbinder, Marat Alimzhanov, Martin Augustin, et al.
Journal of Medicinal Chemistry
|
June 2, 2018
Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors
Neil P Grimster, Erica Anderson, Marat Alimzhanov, et al.
Cell Reports. Medicine
|
March 8, 2023
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice
Rebecca Jarvis, Shu Fun Josephine Ng, Anna J Nathanson, et al.
Journal of Medicinal Chemistry
|
December 23, 2025
Optimization and Chemoproteomic Profiling of a Selective, Covalent Bfl-1-Targeting Cellular Tool
J Henry Blackwell, Simon C C Lucas, Giovanni Battocchio, et al.
ACS Chemical Biology
|
October 19, 2018
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6
William McCoull, Tony Cheung, Erica Anderson, et al.
Page
of 1