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Journal of Medicinal Chemistry|August 23, 2013
Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778)Pratik Devasthale, Ying Wang, Wei Wang, et al.Endocrinology|September 30, 2006
Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in ratsJacek Ostrowski, Joyce E Kuhns, John A Lupisella, et al.Bioorganic & Medicinal Chemistry Letters|February 23, 2008
Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonistsMark E Salvati, Aaron Balog, Weifang Shan, et al.Journal of Medicinal Chemistry|December 22, 2006
Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffoldChongqing Sun, Jeffrey A Robl, Tammy C Wang, et al.Journal of Medicinal Chemistry|June 8, 2007
Discovery of potent and muscle selective androgen receptor modulators through scaffold modificationsJames J Li, James C Sutton, Alexandra Nirschl, et al.Bioorganic & Medicinal Chemistry Letters|February 13, 2007
Tandem optimization of target activity and elimination of mutagenic potential in a potent series of N-aryl bicyclic hydantoin-based selective androgen receptor modulatorsLawrence G Hamann, Mark C Manfredi, Chongqing Sun, et al.Bioorganic & Medicinal Chemistry Letters|September 21, 2017
Discovery of highly potent, selective, covalent inhibitors of JAK3James Kempson, Damaso Ovalle, Junqing Guo, et al.ACS Medicinal Chemistry Letters|January 29, 2016
Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate CancerAudris Huang, Lata Jayaraman, Aberra Fura, et al.ACS Medicinal Chemistry Letters|December 18, 2020
Novel Tricyclic Pyroglutamide Derivatives as Potent RORγt Inverse Agonists Identified using a Virtual Screening ApproachQingjie Liu, Douglas G Batt, Carolyn A Weigelt, et al.Bioorganic & Medicinal Chemistry Letters|May 26, 2017
Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitorsJohn Hynes, Hong Wu, James Kempson, et al.Pageof 5