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Pharmaceutical Research|July 24, 2015
The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients Before and One Year After Bariatric SurgeryMargreke J Brill, Anne van Rongen, Eric P van Dongen, et al.
The AAPS Journal|January 11, 2019
What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision DosingThomas M Polasek, Amin Rostami-Hodjegan, Dong-Seok Yim, et al.
Pharmaceutics|June 27, 2024
Population Pharmacokinetic Analysis and Simulation of Alternative Dosing Regimens for Biosimilars to Adalimumab and Etanercept in Patients with Rheumatoid ArthritisStephanie F Ling, Kayode Ogungbenro, Adam S Darwich, et al.
Annual Review of Pharmacology and Toxicology|October 9, 2020
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug TherapyAdam S Darwich, Thomas M Polasek, Jeffrey K Aronson, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|December 22, 2021
Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspectiveClive G Wilson, Leon Aarons, Patrick Augustijns, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|September 28, 2016
IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compoundsAlison Margolskee, Adam S Darwich, Xavier Pepin, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|November 7, 2016
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of resultsAlison Margolskee, Adam S Darwich, Xavier Pepin, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|October 4, 2016
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classesAdam S Darwich, Alison Margolskee, Xavier Pepin, et al.
European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V|August 18, 2020
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategiesAmais Ahmad, Xavier Pepin, Leon Aarons, et al.
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