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Cellular and Molecular Life Sciences : CMLS
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January 16, 2023
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions
Weiting Tang, Jacob T Beckley, Jin Zhang, et al.
British Journal of Pharmacology
|
September 12, 2023
Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors
Jacob T Beckley, Teresa K Aman, Michael A Ackley, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 30, 2010
Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia
Yinfa Yan, Ping Zhou, David P Rotella, et al.
Journal of Medicinal Chemistry
|
February 25, 2014
Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders
Peng Li, Qiang Zhang, Albert J Robichaud, et al.
Bioorganic & Medicinal Chemistry
|
June 16, 2009
Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT(6) agonists
Ronald C Bernotas, Steven Lenicek, Schuyler Antane, et al.
Journal of Medicinal Chemistry
|
October 12, 2010
5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists
Kevin G Liu, Albert J Robichaud, Ronald C Bernotas, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 13, 2010
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors
Michael S Malamas, Keith Barnes, Yu Hui, et al.
Journal of Medicinal Chemistry
|
July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment
Matthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.
Journal of Medicinal Chemistry
|
August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity
Daniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.
Journal of Medicinal Chemistry
|
March 24, 2015
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
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Search research articles
Search
Showing results (31-40 of 54) with videos related to
Sort By:
Page
of 6
Cellular and Molecular Life Sciences : CMLS
|
January 16, 2023
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions
Weiting Tang, Jacob T Beckley, Jin Zhang, et al.
British Journal of Pharmacology
|
September 12, 2023
Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors
Jacob T Beckley, Teresa K Aman, Michael A Ackley, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 30, 2010
Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophrenia
Yinfa Yan, Ping Zhou, David P Rotella, et al.
Journal of Medicinal Chemistry
|
February 25, 2014
Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders
Peng Li, Qiang Zhang, Albert J Robichaud, et al.
Bioorganic & Medicinal Chemistry
|
June 16, 2009
Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT(6) agonists
Ronald C Bernotas, Steven Lenicek, Schuyler Antane, et al.
Journal of Medicinal Chemistry
|
October 12, 2010
5-Piperazinyl-3-sulfonylindazoles as potent and selective 5-hydroxytryptamine-6 antagonists
Kevin G Liu, Albert J Robichaud, Ronald C Bernotas, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 13, 2010
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors
Michael S Malamas, Keith Barnes, Yu Hui, et al.
Journal of Medicinal Chemistry
|
July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment
Matthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.
Journal of Medicinal Chemistry
|
August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity
Daniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.
Journal of Medicinal Chemistry
|
March 24, 2015
Neuroactive Steroids. 1. Positive Allosteric Modulators of the (γ-Aminobutyric Acid)A Receptor: Structure-Activity Relationships of Heterocyclic Substitution at C-21
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Page
of 6