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Science Signaling
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May 24, 2018
The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms
Luke J Fulcher, Polyxeni Bozatzi, Theresa Tachie-Menson, et al.
Elife
|
July 25, 2023
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
Anna Castano, Margaux Silvestre, Carrow I Wells, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
May 30, 2013
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states
Chitra A Shintre, Ashley C W Pike, Qiuhong Li, et al.
Communications Biology
|
May 18, 2019
ALK2 inhibitors display beneficial effects in preclinical models of <i>ACVR1</i> mutant diffuse intrinsic pontine glioma
Diana Carvalho, Kathryn R Taylor, Nagore Gene Olaciregui, et al.
Journal of Medicinal Chemistry
|
November 21, 2024
Covalent Inhibitors of KEAP1 with Exquisite Selectivity
Imre Fejes, Piroska Markacz, Janos Tatai, et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|
September 9, 2015
Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases
Celia L Gregson, Lawrie Wheeler, Sarah A Hardcastle, et al.
Angewandte Chemie (International Ed. in English)
|
August 21, 2025
Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction
Chunyu Lin, Dilip Narayanan, Marilia Barreca, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma
David Smil, Jong Fu Wong, Eleanor P Williams, et al.
Journal of Medicinal Chemistry
|
July 18, 2024
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2
Václav Němec, Marek Remeš, Petr Beňovský, et al.
Proteins
|
August 24, 2019
Target highlights in CASP13: Experimental target structures through the eyes of their authors
Rosalba Lepore, Andriy Kryshtafovych, Markus Alahuhta, et al.
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Search research articles
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Showing results (101-110 of 115) with videos related to
Sort By:
Page
of 12
Science Signaling
|
May 24, 2018
The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms
Luke J Fulcher, Polyxeni Bozatzi, Theresa Tachie-Menson, et al.
Elife
|
July 25, 2023
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
Anna Castano, Margaux Silvestre, Carrow I Wells, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
May 30, 2013
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states
Chitra A Shintre, Ashley C W Pike, Qiuhong Li, et al.
Communications Biology
|
May 18, 2019
ALK2 inhibitors display beneficial effects in preclinical models of <i>ACVR1</i> mutant diffuse intrinsic pontine glioma
Diana Carvalho, Kathryn R Taylor, Nagore Gene Olaciregui, et al.
Journal of Medicinal Chemistry
|
November 21, 2024
Covalent Inhibitors of KEAP1 with Exquisite Selectivity
Imre Fejes, Piroska Markacz, Janos Tatai, et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|
September 9, 2015
Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases
Celia L Gregson, Lawrie Wheeler, Sarah A Hardcastle, et al.
Angewandte Chemie (International Ed. in English)
|
August 21, 2025
Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction
Chunyu Lin, Dilip Narayanan, Marilia Barreca, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma
David Smil, Jong Fu Wong, Eleanor P Williams, et al.
Journal of Medicinal Chemistry
|
July 18, 2024
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2
Václav Němec, Marek Remeš, Petr Beňovský, et al.
Proteins
|
August 24, 2019
Target highlights in CASP13: Experimental target structures through the eyes of their authors
Rosalba Lepore, Andriy Kryshtafovych, Markus Alahuhta, et al.
Page
of 12