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Expert Opinion on Drug Discovery|October 16, 2018
High-throughput drug screens for amyotrophic lateral sclerosis drug discoveryAlexander McGown, Matthew John Stopford
Molecular Neurodegeneration|July 28, 2016
ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosisAlexander McGown, Dame Pamela J Shaw, Tennore Ramesh
Multiple Sclerosis (Houndmills, Basingstoke, England)|October 16, 2018
Animal models of multiple sclerosis: From rodents to zebrafishDavid John Burrows, Alexander McGown, Saurabh A Jain, et al.
Annals of Neurology|August 31, 2024
RAN Translation of C9orf72-Related Dipeptide Repeat Proteins in Zebrafish Recapitulates Hallmarks of Amyotrophic Lateral Sclerosis and Identifies Hypothermia as a Therapeutic StrategyDavid J Burrows, Alexander McGown, Olfat Abduljabbar, et al.
Acta Neuropathologica Communications|November 21, 2018
Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological featuresMatthew P Shaw, Adrian Higginbottom, Alexander McGown, et al.
Annals of Neurology|January 3, 2013
Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish modelAlexander McGown, Jonathan R McDearmid, Niki Panagiotaki, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|November 7, 2018
The effect of hyperglycemia on neurovascular coupling and cerebrovascular patterning in zebrafishKarishma Chhabria, Karen Plant, Oliver Bandmann, et al.
Brain Communications|April 20, 2022
Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosisSarah Boddy, Mahjabin Islam, Tobias Moll, et al.
Nature Communications|January 8, 2025
Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivoLiam Kempthorne, Deniz Vaizoglu, Alexander J Cammack, et al.
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