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International Journal of Molecular Sciences|March 29, 2023
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1Alexandra L Zakharenko, Olga A Luzina, Arina A Chepanova, et al.Molecular Diversity|September 29, 2016
A versatile strategy for the design and synthesis of novel ADP conjugates and their evaluation as potential poly(ADP-ribose) polymerase 1 inhibitorsYuliya V Sherstyuk, Alexandra L Zakharenko, Mikhail M Kutuzov, et al.Journal of Molecular Modeling|November 10, 2011
Hit clustering can improve virtual fragment screening: CDK2 and PARP1 case studiesAlexey A Zeifman, Victor S Stroylov, Fedor N Novikov, et al.Molecules (Basel, Switzerland)|February 10, 2024
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular ModelingOksana V Salomatina, Tatyana E Kornienko, Alexandra L Zakharenko, et al.Molecules (Basel, Switzerland)|April 3, 2021
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 InhibitorsElizaveta D Gladkova, Arina A Chepanova, Ekaterina S Ilina, et al.International Journal of Molecular Sciences|October 29, 2025
Validating TDP1 as an Inhibition Target for Lipophilic Nucleoside Derivative in Human CellsIrina A Chernyshova, Tatyana E Kornienko, Nadezhda S Dyrkheeva, et al.Biochimica Et Biophysica Acta. General Subjects|April 15, 2024
Transcriptomic analysis of HEK293A cells with a CRISPR/Cas9-mediated TDP1 knockoutNadezhda S Dyrkheeva, Alexandra L Zakharenko, Anastasia A Malakhova, et al.Molecules (Basel, Switzerland)|August 23, 2020
Inhibition of Tyrosyl-DNA Phosphodiesterase 1 by Lipophilic Pyrimidine NucleosidesAlexandra L Zakharenko, Mikhail S Drenichev, Nadezhda S Dyrkheeva, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|September 8, 2018
Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapyAnastasia O Komarova, Mikhail S Drenichev, Nadezhda S Dyrkheeva, et al.Bioorganic & Medicinal Chemistry Letters|July 30, 2022
Monoterpene substituted thiazolidin-4-ones as novel TDP1 inhibitors: Synthesis, biological evaluation and dockingDmitry I Ivankin, Nadezhda S Dyrkheeva, Alexandra L Zakharenko, et al.Pageof 4