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ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein InteractionLeifeng Cheng, Daniel Pettersen, Bengt Ohlsson, et al.Iscience|August 22, 2024
Multi-omic analysis reveals VEGFR2, PI3K, and JNK mediate the small molecule induction of human iPSC-derived cardiomyocyte proliferationLaura A Woo, Kaitlyn L Wintruba, Bethany Wissmann, et al.Journal of Medicinal Chemistry|March 15, 2019
Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery DiseaseDaniel Pettersen, Johan Broddefalk, Hans Emtenäs, et al.Journal of Medicinal Chemistry|December 6, 2014
Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseasesMalin Lemurell, Johan Ulander, Susanne Winiwarter, et al.Nature Reviews. Drug Discovery|December 6, 2019
Rethinking drug design in the artificial intelligence eraPetra Schneider, W Patrick Walters, Alleyn T Plowright, et al.Chemical Communications (Cambridge, England)|September 15, 2017
Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinantsCristina N Alexandru-Crivac, Christian Umeobika, Niina Leikoski, et al.Cell Stem Cell|April 2, 2019
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate PathwayRichard J Mills, Benjamin L Parker, Gregory A Quaife-Ryan, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|December 21, 2020
Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic SteatohepatitisAnurag Mishra, Tamara R Castañeda, Erik Bader, et al.Journal of Medicinal Chemistry|April 3, 2018
Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1Thomas Durek, Philipp M Cromm, Andrew M White, et al.Nature Communications|October 28, 2020
A protein tertiary structure mimetic modulator of the Hippo signalling pathwayHélène Adihou, Ranganath Gopalakrishnan, Tim Förster, et al.Pageof 5