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Current Drug Metabolism
|
October 27, 2010
Methodologies for investigating drug metabolism at the early drug discovery stage: prediction of hepatic drug clearance and P450 contribution
Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, et al.
European Journal of Clinical Pharmacology
|
January 12, 2013
Application of in vitro-in vivo extrapolation (IVIVE) and physiologically based pharmacokinetic (PBPK) modelling to investigate the impact of the CYP2C8 polymorphism on rosiglitazone exposure
Karen Rowland Yeo, Jane R Kenny, Amin Rostami-Hodjegan
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 4, 2014
Deciding on success criteria for predictability of pharmacokinetic parameters from in vitro studies: an analysis based on in vivo observations
Khaled Abduljalil, Theresa Cain, Helen Humphries, et al.
Biopharmaceutics & Drug Disposition
|
March 24, 2021
Scientific considerations to move towards biowaiver for biopharmaceutical classification system class III drugs: How modeling and simulation can help
Fang Wu, Rodrigo Cristofoletti, Liang Zhao, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 2, 2016
Novel minimal physiologically-based model for the prediction of passive tubular reabsorption and renal excretion clearance
Daniel Scotcher, Christopher Jones, Amin Rostami-Hodjegan, et al.
Expert Opinion on Drug Metabolism & Toxicology
|
November 23, 2018
Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics
Martyn Howard, Jill Barber, Naved Alizai, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
February 19, 2019
The nested enzyme-within-enterocyte (NEWE) turnover model for predicting dynamic drug and disease effects on the gut wall
Adam S Darwich, Howard J Burt, Amin Rostami-Hodjegan
The AAPS Journal
|
January 6, 2022
Proof of Concept in Assignment of Within-Subject Variability During Virtual Bioequivalence Studies: Propagation of Intra-Subject Variation in Gastrointestinal Physiology Using Physiologically Based Pharmacokinetic Modeling
Margareta Bego, Nikunjkumar Patel, Rodrigo Cristofoletti, et al.
Journal of Clinical Pharmacology
|
January 31, 2026
Addressing a Common Misconception of Simple Additive and Cumulative Drug Inhibition: Multiple Weak Inhibitors of Common Metabolic Pathway Do Not Pose a Strong Interaction Risk!
Daniel Scotcher, Avijit Ghosh, Aleksandra Galetin, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 26, 2025
Sex-dependent outcomes of bioequivalence studies in the absence of any sex-by-formulation effects on the drug absorption: Examining theoretical possibilities
Maitri Sanghavi, Anyu Lin, Elliot Warwick, et al.
Page
of 31
Search research articles
Search
Showing results (51-60 of 305) with videos related to
Sort By:
Page
of 31
Current Drug Metabolism
|
October 27, 2010
Methodologies for investigating drug metabolism at the early drug discovery stage: prediction of hepatic drug clearance and P450 contribution
Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, et al.
European Journal of Clinical Pharmacology
|
January 12, 2013
Application of in vitro-in vivo extrapolation (IVIVE) and physiologically based pharmacokinetic (PBPK) modelling to investigate the impact of the CYP2C8 polymorphism on rosiglitazone exposure
Karen Rowland Yeo, Jane R Kenny, Amin Rostami-Hodjegan
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 4, 2014
Deciding on success criteria for predictability of pharmacokinetic parameters from in vitro studies: an analysis based on in vivo observations
Khaled Abduljalil, Theresa Cain, Helen Humphries, et al.
Biopharmaceutics & Drug Disposition
|
March 24, 2021
Scientific considerations to move towards biowaiver for biopharmaceutical classification system class III drugs: How modeling and simulation can help
Fang Wu, Rodrigo Cristofoletti, Liang Zhao, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 2, 2016
Novel minimal physiologically-based model for the prediction of passive tubular reabsorption and renal excretion clearance
Daniel Scotcher, Christopher Jones, Amin Rostami-Hodjegan, et al.
Expert Opinion on Drug Metabolism & Toxicology
|
November 23, 2018
Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics
Martyn Howard, Jill Barber, Naved Alizai, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
February 19, 2019
The nested enzyme-within-enterocyte (NEWE) turnover model for predicting dynamic drug and disease effects on the gut wall
Adam S Darwich, Howard J Burt, Amin Rostami-Hodjegan
The AAPS Journal
|
January 6, 2022
Proof of Concept in Assignment of Within-Subject Variability During Virtual Bioequivalence Studies: Propagation of Intra-Subject Variation in Gastrointestinal Physiology Using Physiologically Based Pharmacokinetic Modeling
Margareta Bego, Nikunjkumar Patel, Rodrigo Cristofoletti, et al.
Journal of Clinical Pharmacology
|
January 31, 2026
Addressing a Common Misconception of Simple Additive and Cumulative Drug Inhibition: Multiple Weak Inhibitors of Common Metabolic Pathway Do Not Pose a Strong Interaction Risk!
Daniel Scotcher, Avijit Ghosh, Aleksandra Galetin, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 26, 2025
Sex-dependent outcomes of bioequivalence studies in the absence of any sex-by-formulation effects on the drug absorption: Examining theoretical possibilities
Maitri Sanghavi, Anyu Lin, Elliot Warwick, et al.
Page
of 31