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Journal of Medicinal Chemistry
|
March 28, 2018
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins
Aline D de Araujo, Junxian Lim, Kai-Chen Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 21, 2009
Synthesis and SAR of hydroxyethylamine based phenylcarboxyamides as inhibitors of BACE
Yong-Jin Wu, Yunhui Zhang, Andrew C Good, et al.
Journal of Molecular Graphics & Modelling
|
June 12, 2003
Analysis and optimization of structure-based virtual screening protocols. 2. Examination of docked ligand orientation sampling methodology: mapping a pharmacophore for success
Andrew C Good, Daniel L Cheney, Doree F Sitkoff, et al.
Organic Letters
|
December 6, 2002
Pyrrolidine-5,5-trans-lactams. 2. The use of X-ray crystal structure data in the optimization of P3 and P4 substituents
David M Andrews, Helene Chaignot, Barry A Coomber, et al.
Journal of Medicinal Chemistry
|
February 18, 2010
Molecular shape and medicinal chemistry: a perspective
Anthony Nicholls, Georgia B McGaughey, Robert P Sheridan, et al.
Journal of Medicinal Chemistry
|
February 21, 2012
Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design
Andrew C Good, Jinyu Liu, Bradford Hirth, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 25, 2016
Structure-activity relationships of 4-hydroxy-4-biaryl-proline acylsulfonamide tripeptides: A series of potent NS3 protease inhibitors for the treatment of hepatitis C virus
Alan Xiangdong Wang, Jie Chen, Qian Zhao, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2013
HCV NS5A replication complex inhibitors. Part 5: discovery of potent and pan-genotypic glycinamide cap derivatives
Makonen Belema, Van N Nguyen, Denis R St Laurent, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 20, 2015
Discovery, design, and synthesis of indole-based EZH2 inhibitors
Victor S Gehling, Rishi G Vaswani, Christopher G Nasveschuk, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 14, 2018
P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor
Brian L Venables, Ny Sin, Alan Xiangdong Wang, et al.
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of 4
Search research articles
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Showing results (11-20 of 34) with videos related to
Sort By:
Page
of 4
Journal of Medicinal Chemistry
|
March 28, 2018
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins
Aline D de Araujo, Junxian Lim, Kai-Chen Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 21, 2009
Synthesis and SAR of hydroxyethylamine based phenylcarboxyamides as inhibitors of BACE
Yong-Jin Wu, Yunhui Zhang, Andrew C Good, et al.
Journal of Molecular Graphics & Modelling
|
June 12, 2003
Analysis and optimization of structure-based virtual screening protocols. 2. Examination of docked ligand orientation sampling methodology: mapping a pharmacophore for success
Andrew C Good, Daniel L Cheney, Doree F Sitkoff, et al.
Organic Letters
|
December 6, 2002
Pyrrolidine-5,5-trans-lactams. 2. The use of X-ray crystal structure data in the optimization of P3 and P4 substituents
David M Andrews, Helene Chaignot, Barry A Coomber, et al.
Journal of Medicinal Chemistry
|
February 18, 2010
Molecular shape and medicinal chemistry: a perspective
Anthony Nicholls, Georgia B McGaughey, Robert P Sheridan, et al.
Journal of Medicinal Chemistry
|
February 21, 2012
Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design
Andrew C Good, Jinyu Liu, Bradford Hirth, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 25, 2016
Structure-activity relationships of 4-hydroxy-4-biaryl-proline acylsulfonamide tripeptides: A series of potent NS3 protease inhibitors for the treatment of hepatitis C virus
Alan Xiangdong Wang, Jie Chen, Qian Zhao, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2013
HCV NS5A replication complex inhibitors. Part 5: discovery of potent and pan-genotypic glycinamide cap derivatives
Makonen Belema, Van N Nguyen, Denis R St Laurent, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 20, 2015
Discovery, design, and synthesis of indole-based EZH2 inhibitors
Victor S Gehling, Rishi G Vaswani, Christopher G Nasveschuk, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 14, 2018
P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor
Brian L Venables, Ny Sin, Alan Xiangdong Wang, et al.
Page
of 4