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Journal of Medicinal Chemistry
|
January 5, 2002
Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality
Alan D Borthwick, Andrew J Crame, Peter F Ertl, et al.
ACS Chemical Biology
|
November 30, 2017
Design and Application of a DNA-Encoded Macrocyclic Peptide Library
Zhengrong Zhu, Alex Shaginian, LaShadric C Grady, et al.
Pharmacology Research & Perspectives
|
December 14, 2019
MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions
Jak Grimes, Sapna Desai, Neil W Charter, et al.
Journal of Medicinal Chemistry
|
January 14, 2012
Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency
Alan D Borthwick, John Liddle, Dave E Davies, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 16, 2006
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors
Nigel S Watson, David Brown, Matthew Campbell, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2007
The discovery of GSK221149A: a potent and selective oxytocin antagonist
John Liddle, Michael J Allen, Alan D Borthwick, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2006
Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs
Robert J Young, Matthew Campbell, Alan D Borthwick, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioconjugate Chemistry
|
February 1, 2021
<i>In Vivo</i> Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders
Julien C Vantourout, Andrew M Mason, Josephine Yuen, et al.
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Showing results (11-20 of 20) with videos related to
Sort By:
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You have reached the last page of results.
This site can display upto 20 results.
Journal of Medicinal Chemistry
|
January 5, 2002
Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality
Alan D Borthwick, Andrew J Crame, Peter F Ertl, et al.
ACS Chemical Biology
|
November 30, 2017
Design and Application of a DNA-Encoded Macrocyclic Peptide Library
Zhengrong Zhu, Alex Shaginian, LaShadric C Grady, et al.
Pharmacology Research & Perspectives
|
December 14, 2019
MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions
Jak Grimes, Sapna Desai, Neil W Charter, et al.
Journal of Medicinal Chemistry
|
January 14, 2012
Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency
Alan D Borthwick, John Liddle, Dave E Davies, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 16, 2006
Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors
Nigel S Watson, David Brown, Matthew Campbell, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2007
The discovery of GSK221149A: a potent and selective oxytocin antagonist
John Liddle, Michael J Allen, Alan D Borthwick, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 20, 2006
Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs
Robert J Young, Matthew Campbell, Alan D Borthwick, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 7, 2007
Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs
Robert J Young, Alan D Borthwick, David Brown, et al.
Bioconjugate Chemistry
|
February 1, 2021
<i>In Vivo</i> Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders
Julien C Vantourout, Andrew M Mason, Josephine Yuen, et al.
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of 2