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Nature Biotechnology|October 5, 2021
Engineered pegRNAs improve prime editing efficiencyJames W Nelson, Peyton B Randolph, Simon P Shen, et al.Nature Biotechnology|May 4, 2023
Efficient prime editing in mouse brain, liver and heart with dual AAVsJessie R Davis, Samagya Banskota, Jonathan M Levy, et al.Nature Biotechnology|June 29, 2021
Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learningLuke W Koblan, Mandana Arbab, Max W Shen, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a potent inhibitor of anaplastic lymphoma kinase with in vivo antitumor activityGregory R Ott, Rabindranath Tripathy, Mangeng Cheng, et al.Bioorganic & Medicinal Chemistry Letters|November 16, 2010
Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse modelsEugen F Mesaros, Jason P Burke, Jonathan D Parrish, et al.Nature Biotechnology|May 11, 2023
A prime editor mouse to model a broad spectrum of somatic mutations in vivoZackery A Ely, Nicolas Mathey-Andrews, Santiago Naranjo, et al.The New England Journal of Medicine|December 8, 2025
Prime Editing for p47phox-Deficient Chronic Granulomatous DiseaseJennifer L Gori, Elie Haddad, Haydar Frangoul, et al.Pageof 2