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British Journal of Pharmacology|December 23, 2017
Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3Martyna Szpakowska, Amanda M Nevins, Max Meyrath, et al.
Cell|April 24, 2025
Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction networkAndrew B Kleist, Martyna Szpakowska, Lindsay J Talbot, et al.
Science (New York, N.Y.)|July 20, 2022
Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptorAndrew B Kleist, Shawn Jenjak, Andrija Sente, et al.
Molecular Cell|February 20, 2025
Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2Shirsha Saha, Fumiya K Sano, Saloni Sharma, et al.
JCI Insight|March 8, 2023
Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndromeRajesh Kumar, Samantha Milanesi, Martyna Szpakowska, et al.
Cell Communication and Signaling : CCS|May 20, 2025
GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migrationDan Pascal Jean Albers, Sofya Novikova, Julio Vieyto-Nuñez, et al.
Cell Reports|January 14, 2023
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptorsAnna L Gray, Richard Karlsson, Abigail R E Roberts, et al.
Nature Communications|November 19, 2022
How Carvedilol activates β2-adrenoceptorsTobias Benkel, Mirjam Zimmermann, Julian Zeiner, et al.
Cancers|October 13, 2021
Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease ModelAdam M Passman, Robyn P Strauss, Sarah B McSpadden, et al.
Molecular Pharmacology|February 12, 2024
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3Aurelien M Zarca, Ilze Adlere, Cristina P Viciano, et al.
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