Showing results (1-10 of 51) with videos related to
Sort By:
Pageof 6
FEBS Letters|May 26, 2019
Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugsEmma Scaletti, Ann-Sofie Jemth, Thomas Helleday, et al.Biochemistry|January 8, 2019
Crystal Structure and Substrate Specificity of the 8-oxo-dGTP Hydrolase NUDT1 from Arabidopsis thalianaAnn-Sofie Jemth, Emma Scaletti, Megan Carter, et al.Journal of Molecular Biology|January 19, 2020
The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and ProductsEmma Scaletti, Magnus Claesson, Thomas Helleday, et al.Journal of the American Chemical Society|March 19, 2010
CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymeraseNicola Ramsay, Ann-Sofie Jemth, Anthony Brown, et al.The Journal of Biological Chemistry|June 22, 2022
Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravirAnn-Sofie Jemth, Emma Rose Scaletti, Evert Homan, et al.Nucleosides, Nucleotides & Nucleic Acids|June 3, 2024
The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342Christopher Dirks, Henri Colyn Bwanika, Ann-Sofie Jemth, et al.Biochemistry|December 28, 2017
Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in AffinityMohit Narwal, Ann-Sofie Jemth, Robert Gustafsson, et al.FEBS Letters|July 27, 2011
Crystal structure of human MTH1 and the 8-oxo-dGMP product complexLinda M Svensson, Ann-Sofie Jemth, Matthieu Desroses, et al.The Journal of Biological Chemistry|January 13, 2010
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNAOlga Loseva, Ann-Sofie Jemth, Helen E Bryant, et al.The Journal of Biological Chemistry|February 28, 2026
A monofunctional-like mutant of DNA glycosylase NTHL1 changes the dynamics of DNA repair during acute oxidative stressJames Haslam, Natalie Rudolfova, Kaixin Zhou, et al.Pageof 6