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Neurobiology of Disease|December 24, 2017
A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibilityChristopher J Yuskaitis, Brandon M Jones, Rachel L Wolfson, et al.
Cell Metabolism|May 7, 2020
A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin SecretionAharon Helman, Andrew L Cangelosi, Jeffrey C Davis, et al.
Molecular Cell|April 30, 2003
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTORDo-Hyung Kim, D D Sarbassov, Siraj M Ali, et al.
ACS Chemical Biology|April 13, 2012
Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiaeQingsong Liu, Tao Ren, Tara Fresques, et al.
Cell|October 21, 2017
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a NutrientGregory A Wyant, Monther Abu-Remaileh, Rachel L Wolfson, et al.
Elife|September 27, 2023
High-content microscopy reveals a morphological signature of bortezomib resistanceMegan E Kelley, Adi Y Berman, David R Stirling, et al.
Molecular Biology of the Cell|May 6, 2025
Live Cell Painting: image-based profiling in live cells using Acridine OrangeFernanda Garcia-Fossa, Thaís Moraes-Lacerda, Mariana Rodrigues-da-Silva, et al.
Biorxiv : the Preprint Server for Biology|September 11, 2024
Live Cell Painting: image-based profiling in live cells using Acridine OrangeFernanda Garcia-Fossa, Thaís Moraes-Lacerda, Mariana Rodrigues-da-Silva, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 23, 2021
Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunctionKendall J Condon, Jose M Orozco, Charles H Adelmann, et al.
Nature|March 28, 2014
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanidesKıvanç Birsoy, Richard Possemato, Franziska K Lorbeer, et al.
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