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Cancer Biology & Therapy|December 7, 2007
Response and determinants of cancer cell susceptibility to PI3K inhibitors: combined targeting of PI3K and Mek1 as an effective anticancer strategyKer Yu, Lourdes Toral-Barza, Celine Shi, et al.Bioorganic & Medicinal Chemistry Letters|November 10, 2009
Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3KJeroen C Verheijen, Ker Yu, Lourdes Toral-Barza, et al.Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Absolute configurations of tubulin inhibitors taltobulin (HTI-286) and HTI-042 characterized by X-ray diffraction analysis and NMR studiesChuansheng Niu, Douglas M Ho, Robert Thomas Williamson, et al.Bioorganic & Medicinal Chemistry Letters|March 13, 2010
2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stabilityJeroen C Verheijen, David J Richard, Kevin Curran, et al.Journal of the American Chemical Society|August 12, 2004
Probing the interaction of HTI-286 with tubulin using a stilbene analogueMei-Chu Lo, Ann Aulabaugh, Girija Krishnamurthy, et al.Bioorganic & Medicinal Chemistry Letters|December 8, 2009
Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)Joshua Kaplan, Jeroen C Verheijen, Natasja Brooijmans, et al.Bioorganic & Medicinal Chemistry Letters|July 21, 2004
Tubulin inhibitors. Synthesis and biological activity of HTI-286 analogs with B-segment heterosubstituentsChuan Niu, Daniel Smith, Arie Zask, et al.Biochemistry|November 19, 2003
Biophysical characterization of the interactions of HTI-286 with tubulin heterodimer and microtubulesGirija Krishnamurthy, Wendy Cheng, Mei-Chu Lo, et al.ACS Medicinal Chemistry Letters|December 20, 2023
Kinases Controlling Stability of the Oncogenic MYCN ProteinNailah Smith, Eduard Reznik, Brygida Bisikirska, et al.Journal of Natural Products|January 26, 2013
Synthesis of antioxidants for prevention of age-related macular degenerationDharati Joshi, James Field, John Murphy, et al.Pageof 6