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Science Translational Medicine|April 29, 2021
SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse modelsAxel Hyrenius-Wittsten, Yang Su, Minhee Park, et al.Cell|April 15, 2022
Modular design of synthetic receptors for programmed gene regulation in cell therapiesIowis Zhu, Raymond Liu, Julie M Garcia, et al.Biochemistry|September 22, 2011
The structural role of N-linked glycans on human glypican-1Gabriel Svensson, Axel Hyrenius Wittsten, Sara Linse, et al.Blood|October 1, 2014
HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemiaTalia Velasco-Hernandez, Axel Hyrenius-Wittsten, Matilda Rehn, et al.Science Signaling|July 29, 2010
Inhibiting the inhibitor of the inhibitor: blocking PKC-theta to enhance regulatory T cell functionKole T Roybal, Christoph WülfingAnnual Review of Immunology|April 28, 2017
Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic CapabilitiesKole T Roybal, Wendell A LimBlood Advances|April 4, 2024
CD4+ CAR T-cell exhaustion associated with early relapse of multiple myeloma after BCMA CAR T-cell therapyGuy Ledergor, Zenghua Fan, Kai Wu, et al.Biorxiv : the Preprint Server for Biology|February 6, 2026
Synthetic Hybrid Receptors for Safer and Programmable T Cell TherapyMaxwell G Foisey, Julie Garcia, Xun Li, et al.Communicative & Integrative Biology|February 19, 2011
Tentative and transient natural killer cell polarization balances the requirements for discriminatory recognition and cytolytic efficacyParisa Sinai, Kole T Roybal, Christoph WülfingPageof 6