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Journal of Immunology (Baltimore, Md. : 1950)|May 9, 1998
Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergyD R DeSilva, E A Jones, M F Favata, et al.Biochemical and Biophysical Research Communications|February 19, 2000
Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivoB D Jaffee, E J Manos, R J Collins, et al.Osteoarthritis and Cartilage|November 26, 2008
Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradationA M Malfait, M Tortorella, J Thompson, et al.Bioorganic & Medicinal Chemistry Letters|January 5, 1999
Heteroatom- and carbon-linked biphenyl analogs of Brequinar as immunosuppressive agentsD G Batt, J J Petraitis, S R Sherk, et al.Nature|November 23, 1995
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase IIJ E Dinchuk, B D Car, R J Focht, et al.Bioorganic & Medicinal Chemistry Letters|May 26, 1999
Macrocyclic hydroxamate inhibitors of matrix metalloproteinases and TNF-alpha productionR J Cherney, L Wang, D T Meyer, et al.Journal of Medicinal Chemistry|October 5, 2001
Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1', a series of selective TNF-alpha converting enzyme inhibitors with potent cellular activity in the inhibition of TNF-alpha releaseC B Xue, X He, R L Corbett, et al.Bioorganic & Medicinal Chemistry Letters|January 1, 1999
Structure-activity relationships (SAR) of some tetracyclic heterocycles related to the immunosuppressive agent Brequinar SodiumW J Pitts, J W Jetter, D J Pinto, et al.Journal of Medicinal Chemistry|July 27, 2001
Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivoC B Xue, M E Voss, D J Nelson, et al.Pageof 2