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Journal of Medicinal Chemistry
|
August 5, 2024
Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent <i>In Vivo</i> Activities in Mouse Models of Hematological and Solid Tumors
James C Tarr, James M Salovich, Martin Aichinger, et al.
Antimicrobial Agents and Chemotherapy
|
November 25, 2004
Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen
Simon J F Macdonald, Keith G Watson, Rachel Cameron, et al.
Journal of Medicinal Chemistry
|
April 15, 2005
Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza
Simon J F Macdonald, Rachel Cameron, Derek A Demaine, et al.
Journal of Medicinal Chemistry
|
March 15, 2021
One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRAS
Juergen Ramharter, Dirk Kessler, Peter Ettmayer, et al.
Cancer Discovery
|
August 21, 2020
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Marco H Hofmann, Michael Gmachl, Juergen Ramharter, et al.
Journal of Medicinal Chemistry
|
November 6, 2019
Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors
Harald Engelhardt, Dietrich Böse, Mark Petronczki, et al.
Nature Chemical Biology
|
June 11, 2019
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
William Farnaby, Manfred Koegl, Michael J Roy, et al.
Nature Chemical Biology
|
July 4, 2019
Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
William Farnaby, Manfred Koegl, Michael J Roy, et al.
Journal of Medicinal Chemistry
|
August 1, 2019
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor <b>BI-4924</b> Disrupts Serine Biosynthesis
Harald Weinstabl, Matthias Treu, Joerg Rinnenthal, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 24, 2019
Drugging an undruggable pocket on KRAS
Dirk Kessler, Michael Gmachl, Andreas Mantoulidis, et al.
Page
of 24
Search research articles
Search
Showing results (221-230 of 234) with videos related to
Sort By:
Page
of 24
Journal of Medicinal Chemistry
|
August 5, 2024
Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent <i>In Vivo</i> Activities in Mouse Models of Hematological and Solid Tumors
James C Tarr, James M Salovich, Martin Aichinger, et al.
Antimicrobial Agents and Chemotherapy
|
November 25, 2004
Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen
Simon J F Macdonald, Keith G Watson, Rachel Cameron, et al.
Journal of Medicinal Chemistry
|
April 15, 2005
Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza
Simon J F Macdonald, Rachel Cameron, Derek A Demaine, et al.
Journal of Medicinal Chemistry
|
March 15, 2021
One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRAS
Juergen Ramharter, Dirk Kessler, Peter Ettmayer, et al.
Cancer Discovery
|
August 21, 2020
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Marco H Hofmann, Michael Gmachl, Juergen Ramharter, et al.
Journal of Medicinal Chemistry
|
November 6, 2019
Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors
Harald Engelhardt, Dietrich Böse, Mark Petronczki, et al.
Nature Chemical Biology
|
June 11, 2019
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
William Farnaby, Manfred Koegl, Michael J Roy, et al.
Nature Chemical Biology
|
July 4, 2019
Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
William Farnaby, Manfred Koegl, Michael J Roy, et al.
Journal of Medicinal Chemistry
|
August 1, 2019
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor <b>BI-4924</b> Disrupts Serine Biosynthesis
Harald Weinstabl, Matthias Treu, Joerg Rinnenthal, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 24, 2019
Drugging an undruggable pocket on KRAS
Dirk Kessler, Michael Gmachl, Andreas Mantoulidis, et al.
Page
of 24