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Current Topics in Medicinal Chemistry
|
April 14, 2007
2'-Modified oligonucleotides for antisense therapeutics
Thazha P Prakash, Balkrishen Bhat
Trends in Molecular Medicine
|
June 26, 2021
mRNA therapeutics: beyond vaccine applications
Balkrishen Bhat, Shrirang Karve, Daniel G Anderson
Nucleic Acids Research
|
July 14, 2010
Solution-state structure of a fully alternately 2'-F/2'-OMe modified 42-nt dimeric siRNA construct
Peter Podbevsek, Charles R Allerson, Balkrishen Bhat, et al.
Nucleosides, Nucleotides & Nucleic Acids
|
March 27, 2004
Synthesis of 2'-substituted MMI linked nucleosidic dimers: an optimization study in search of high affinity oligonucleotides for use in antisense constructs
Didier Peoc'h, Eric E Swayze, Balkrishen Bhat, et al.
Nucleosides, Nucleotides & Nucleic Acids
|
February 26, 2010
Activity of siRNAs with 2-thio-2'-O-methyluridine modification in mammalian cells
Thazha P Prakash, Nishant Naik, Namir Sioufi, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 18, 2006
RNA interference by 2',5'-linked nucleic acid duplexes in mammalian cells
Thazha P Prakash, Bryan Kraynack, Brenda F Baker, et al.
The Journal of Organic Chemistry
|
November 15, 1996
Synthesis of Novel Nucleic Acid Mimics via the Stereoselective Intermolecular Radical Coupling of 3'-Iodo Nucleosides and Formaldoximes(1)
Balkrishen Bhat, Eric E. Swayze, Patrick Wheeler, et al.
RNA (New York, N.Y.)
|
June 29, 2012
Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver
John R Androsavich, B Nelson Chau, Balkrishen Bhat, et al.
Molecular Therapy. Nucleic Acids
|
January 25, 2013
Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals
Punit P Seth, Ali Jazayeri, Jeff Yu, et al.
The Journal of Clinical Investigation
|
February 3, 2011
Comparison of different miR-21 inhibitor chemistries in a cardiac disease model
Thomas Thum, Nelson Chau, Balkrishen Bhat, et al.
Page
of 5
Search research articles
Search
Showing results (1-10 of 44) with videos related to
Sort By:
Page
of 5
Current Topics in Medicinal Chemistry
|
April 14, 2007
2'-Modified oligonucleotides for antisense therapeutics
Thazha P Prakash, Balkrishen Bhat
Trends in Molecular Medicine
|
June 26, 2021
mRNA therapeutics: beyond vaccine applications
Balkrishen Bhat, Shrirang Karve, Daniel G Anderson
Nucleic Acids Research
|
July 14, 2010
Solution-state structure of a fully alternately 2'-F/2'-OMe modified 42-nt dimeric siRNA construct
Peter Podbevsek, Charles R Allerson, Balkrishen Bhat, et al.
Nucleosides, Nucleotides & Nucleic Acids
|
March 27, 2004
Synthesis of 2'-substituted MMI linked nucleosidic dimers: an optimization study in search of high affinity oligonucleotides for use in antisense constructs
Didier Peoc'h, Eric E Swayze, Balkrishen Bhat, et al.
Nucleosides, Nucleotides & Nucleic Acids
|
February 26, 2010
Activity of siRNAs with 2-thio-2'-O-methyluridine modification in mammalian cells
Thazha P Prakash, Nishant Naik, Namir Sioufi, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 18, 2006
RNA interference by 2',5'-linked nucleic acid duplexes in mammalian cells
Thazha P Prakash, Bryan Kraynack, Brenda F Baker, et al.
The Journal of Organic Chemistry
|
November 15, 1996
Synthesis of Novel Nucleic Acid Mimics via the Stereoselective Intermolecular Radical Coupling of 3'-Iodo Nucleosides and Formaldoximes(1)
Balkrishen Bhat, Eric E. Swayze, Patrick Wheeler, et al.
RNA (New York, N.Y.)
|
June 29, 2012
Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver
John R Androsavich, B Nelson Chau, Balkrishen Bhat, et al.
Molecular Therapy. Nucleic Acids
|
January 25, 2013
Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals
Punit P Seth, Ali Jazayeri, Jeff Yu, et al.
The Journal of Clinical Investigation
|
February 3, 2011
Comparison of different miR-21 inhibitor chemistries in a cardiac disease model
Thomas Thum, Nelson Chau, Balkrishen Bhat, et al.
Page
of 5