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Bioorganic & Medicinal Chemistry Letters|May 17, 2017
Recent progress towards clinically relevant ATP-competitive Akt inhibitorsBayard R Huck, Igor MochalkinThe Journal of Organic Chemistry|April 23, 2005
Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomersBayard R Huck, Samuel H GellmanAngewandte Chemie (International Ed. in English)|October 4, 2017
Small Molecules Drive Big Improvements in Immuno-Oncology TherapiesBayard R Huck, Lisa Kötzner, Klaus UrbahnsProtein Science : a Publication of the Protein Society|February 22, 2008
Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitorIgor Mochalkin, John D Knafels, Sandra LightleBiochemistry|October 16, 2002
Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analoguesJonathan R Lai, Bayard R Huck, Bernard Weisblum, et al.Protein Science : a Publication of the Protein Society|December 15, 2012
Protein prosthesis: β-peptides as reverse-turn surrogatesUlrich Arnold, Bayard R Huck, Samuel H Gellman, et al.Journal of the American Chemical Society|September 17, 2004
Secondary structural preferences of 2,2-disubstituted pyrrolidine-4-carboxylic acid oligomers: beta-peptide foldamers that cannot form internal hydrogen bondsBayard R Huck, John D Fisk, Ilia A Guzei, et al.American Journal of Cancer Research|May 18, 2016
M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrierAndreas Machl, Erik W Wilker, Hui Tian, et al.Protein Science : a Publication of the Protein Society|January 26, 2008
Structure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding siteIgor Mochalkin, Sandra Lightle, Lakshmi Narasimhan, et al.Journal of the American Chemical Society|July 18, 2002
Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turnUlrich Arnold, Matthew P Hinderaker, Bradley L Nilsson, et al.Pageof 4