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Journal of Neurochemistry|September 22, 2007
The effects of oxidative stress on parkin and other E3 ligasesMatthew J LaVoie, Giuseppe P Cortese, Beth L Ostaszewski, et al.
Acta Neuropathologica Communications|November 10, 2018
Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer's diseaseShaomin Li, Ming Jin, Lei Liu, et al.
Biochemistry|January 21, 2009
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial traffickingAndreas Weihofen, Kelly Jean Thomas, Beth L Ostaszewski, et al.
Nature Medicine|October 18, 2005
Dopamine covalently modifies and functionally inactivates parkinMatthew J LaVoie, Beth L Ostaszewski, Andreas Weihofen, et al.
The Journal of Biological Chemistry|February 11, 2010
Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substratesAllen C Chen, Lucie Y Guo, Beth L Ostaszewski, et al.
The Journal of Biological Chemistry|July 20, 2002
Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulationW Taylor Kimberly, Matthew J LaVoie, Beth L Ostaszewski, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 13, 2003
Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2W Taylor Kimberly, Matthew J LaVoie, Beth L Ostaszewski, et al.
The Journal of Biological Chemistry|October 21, 2005
gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding sitePatrick C Fraering, Wenjuan Ye, Matthew J LaVoie, et al.
Biochemistry|January 14, 2004
Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complexPatrick C Fraering, Matthew J LaVoie, Wenjuan Ye, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 28, 2002
Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrateWilliam P Esler, W Taylor Kimberly, Beth L Ostaszewski, et al.
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