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Journal of Medicinal Chemistry|October 30, 2023
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin DeacetylationLaura Sinatra, Anja Vogelmann, Florian Friedrich, et al.
The Journal of Experimental Medicine|January 11, 2012
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2Kai B Kaufmann, Albert Gründer, Tobias Hadlich, et al.
Cell Reports|December 22, 2021
Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2Martin Marek, Elizabeth Ramos-Morales, Gisele F A Picchi-Constante, et al.
Journal of Medicinal Chemistry|June 17, 2025
Structure-Guided Design of a KMT9 Inhibitor Prodrug with Cellular ActivitySheng Wang, Nicolas P F Barthes, Sylvia Urban, et al.
ACS Chemical Biology|July 10, 2019
The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone DemethylasesMartin Roatsch, Inga Hoffmann, Martine I Abboud, et al.
ACS Medicinal Chemistry Letters|November 20, 2020
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological EvaluationA Prasanth Saraswati, Nicola Relitti, Margherita Brindisi, et al.
European Journal of Medicinal Chemistry|May 13, 2022
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viabilityStefano Federico, Tuhina Khan, Anna Fontana, et al.
Journal of Medicinal Chemistry|September 25, 2019
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin FunctionVincent Fagan, Catrine Johansson, Carina Gileadi, et al.
Journal of Medicinal Chemistry|May 5, 2026
Development of High-Affinity CHD1 Chromodomain InhibitorsHolger Greschik, Florian Friedrich, Ludwig Seifert, et al.
Journal of Medicinal Chemistry|July 12, 2021
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent InhibitorsGiuseppe Campiani, Caterina Cavella, Jeremy D Osko, et al.
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