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Molecular Cell|December 22, 2015
A Multiplexed System for Quantitative Comparisons of Chromatin LandscapesPeter van Galen, Aaron D Viny, Oren Ram, et al.
Nature Chemical Biology|July 4, 2024
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1Kwangwoon Lee, Marco Barone, Amanda L Waterbury, et al.
Molecular Cell|June 13, 2024
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencingAmanda L Waterbury, Hui Si Kwok, Ceejay Lee, et al.
Biorxiv : the Preprint Server for Biology|May 27, 2024
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor ComplexesXiaowen Xie, Olivia Zhang, Megan J R Yeo, et al.
Nature|February 12, 2025
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutationsXiaowen Xie, Olivia Zhang, Megan J R Yeo, et al.
Cell Stem Cell|December 20, 2016
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug ToleranceBrian B Liau, Cem Sievers, Laura K Donohue, et al.
Cancer Discovery|April 10, 2020
Gain-of-Function Genetic Alterations of G9a Drive OncogenesisShinichiro Kato, Qing Yu Weng, Megan L Insco, et al.
Nature|July 6, 2017
Transcription elongation factors represent in vivo cancer dependencies in glioblastomaTyler E Miller, Brian B Liau, Lisa C Wallace, et al.
Biorxiv : the Preprint Server for Biology|May 27, 2024
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 ComplexesMegan Jr Yeo, Olivia Zhang, Xiaowen Xie, et al.
Nature|September 30, 2015
Mediator kinase inhibition further activates super-enhancer-associated genes in AMLHenry E Pelish, Brian B Liau, Ioana I Nitulescu, et al.
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