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ACS Medicinal Chemistry Letters
|
March 18, 2016
Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI
Joseph E Pero, Michael A Rossi, Michael J Kelly, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 5, 2015
Rapid development of two factor IXa inhibitors from hit to lead
Dann L Parker, Shawn Walsh, Bing Li, et al.
The Journal of Organic Chemistry
|
November 27, 2018
Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor
Yong-Li Zhong, Ed Cleator, Zhijian Liu, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia
John S Debenham, Christina Madsen-Duggan, Matthew J Clements, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 17, 2015
Development of a novel class of potent and selective FIXa inhibitors
Ting Zhang, Patrick Andre, Thomas J Bateman, et al.
Journal of Medicinal Chemistry
|
March 3, 2017
Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1H-benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors
Tim Cernak, Nathan J Gesmundo, Kevin Dykstra, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2017
Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na<sub>v</sub>1.7 inhibitors with pain efficacy in mice
Anthony J Roecker, Melissa Egbertson, Kristen L G Jones, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2016
Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes
Liangqin Guo, Dann L Parker, Yi Zang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 31, 2015
Development of a novel tricyclic class of potent and selective FIXa inhibitors
Dongfang Meng, Patrick Andre, Thomas J Bateman, et al.
Journal of Medicinal Chemistry
|
February 28, 2012
1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia
Petr Vachal, Shouwu Miao, Joan M Pierce, et al.
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of 9
Search research articles
Search
Showing results (71-80 of 81) with videos related to
Sort By:
Page
of 9
ACS Medicinal Chemistry Letters
|
March 18, 2016
Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI
Joseph E Pero, Michael A Rossi, Michael J Kelly, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 5, 2015
Rapid development of two factor IXa inhibitors from hit to lead
Dann L Parker, Shawn Walsh, Bing Li, et al.
The Journal of Organic Chemistry
|
November 27, 2018
Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor
Yong-Li Zhong, Ed Cleator, Zhijian Liu, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia
John S Debenham, Christina Madsen-Duggan, Matthew J Clements, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 17, 2015
Development of a novel class of potent and selective FIXa inhibitors
Ting Zhang, Patrick Andre, Thomas J Bateman, et al.
Journal of Medicinal Chemistry
|
March 3, 2017
Microscale High-Throughput Experimentation as an Enabling Technology in Drug Discovery: Application in the Discovery of (Piperidinyl)pyridinyl-1H-benzimidazole Diacylglycerol Acyltransferase 1 Inhibitors
Tim Cernak, Nathan J Gesmundo, Kevin Dykstra, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2017
Discovery of selective, orally bioavailable, N-linked arylsulfonamide Na<sub>v</sub>1.7 inhibitors with pain efficacy in mice
Anthony J Roecker, Melissa Egbertson, Kristen L G Jones, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2016
Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes
Liangqin Guo, Dann L Parker, Yi Zang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 31, 2015
Development of a novel tricyclic class of potent and selective FIXa inhibitors
Dongfang Meng, Patrick Andre, Thomas J Bateman, et al.
Journal of Medicinal Chemistry
|
February 28, 2012
1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia
Petr Vachal, Shouwu Miao, Joan M Pierce, et al.
Page
of 9