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Journal of Immunology Research|February 25, 2020
In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug DevelopmentObinna C Ubah, Andrew J Porter, Caroline J BarelleFrontiers in Immunology|April 11, 2019
An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease ModelObinna C Ubah, John Steven, Andrew J Porter, et al.Methods in Molecular Biology (Clifton, N.J.)|February 14, 2022
Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic DevelopmentSamata S Pandey, Marina Kovaleva, Caroline J Barelle, et al.Biochemical Society Transactions|October 28, 2021
Development of next generation nanomedicine-based approaches for the treatment of cancer: we've barely scratched the surfaceShannon R Tracey, Peter Smyth, Caroline J Barelle, et al.Protein Engineering, Design & Selection : PEDS|March 3, 2020
Isolation of highly selective IgNAR variable single-domains against a human therapeutic Fc scaffold and their application as tailor-made bioprocessing reagentsMagdalena J Buschhaus, Stefan Becker, Andrew J Porter, et al.Frontiers in Immunology|October 11, 2017
Therapeutic Potential of Shark Anti-ICOSL VNAR Domains is Exemplified in a Murine Model of Autoimmune Non-Infectious UveitisMarina Kovaleva, Katherine Johnson, John Steven, et al.Current Pharmaceutical Design|September 9, 2016
Phage Display Derived IgNAR V Region Binding Domains for Therapeutic DevelopmentObinna C Ubah, Caroline J Barelle, Magdalena J Buschhaus, et al.Mabs|December 20, 2014
Structural insights and biomedical potential of IgNAR scaffolds from sharksStefan Zielonka, Martin Empting, Julius Grzeschik, et al.Eukaryotic Cell|February 10, 2006
Candida albicans VAC8 is required for vacuolar inheritance and normal hyphal branchingCaroline J Barelle, Mathias L Richard, Claude Gaillardin, et al.Frontiers in Immunology|January 10, 2018
Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic DevelopmentObinna C Ubah, John Steven, Marina Kovaleva, et al.Pageof 3