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Clinical Pharmacology in Drug Development
|
November 4, 2022
Population Pharmacokinetics of Oral Migalastat in Adolescents and Adults With and Without Renal Impairment
Cathrine Leonowens, Virginia Schmith, Jie Zhou, et al.
Journal of Clinical Pharmacology
|
January 11, 2014
Population pharmacokinetics of dabrafenib, a BRAF inhibitor: effect of dose, time, covariates, and relationship with its metabolites
Daniele Ouellet, Ekaterina Gibiansky, Cathrine Leonowens, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 26, 2024
MDMA pharmacokinetics: A population and physiologically based pharmacokinetics model-informed analysis
Marilyn A Huestis, William B Smith, Cathrine Leonowens, et al.
Cancer Chemotherapy and Pharmacology
|
March 5, 2016
Population pharmacokinetics and exposure-response of trametinib, a MEK inhibitor, in patients with BRAF V600 mutation-positive melanoma
Daniele Ouellet, Nastya Kassir, Joannellyn Chiu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 28, 2019
Indinavir Increases Midazolam <i>N</i>-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach
Dan-Dan Tian, Cathrine Leonowens, Emily J Cox, et al.
British Journal of Clinical Pharmacology
|
March 11, 2014
Concomitant oral and intravenous pharmacokinetics of trametinib, a MEK inhibitor, in subjects with solid tumours
Cathrine Leonowens, Carolyn Pendry, John Bauman, et al.
Journal of Clinical Anesthesia
|
June 26, 2020
Population pharmacokinetic/pharmacodynamic modeling for remimazolam in the induction and maintenance of general anesthesia in healthy subjects and in surgical subjects
Jie Zhou, Cathrine Leonowens, Vijay D Ivaturi, et al.
Cancer Research Communications
|
November 12, 2024
Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma
Todd Shearer, Melissa Comstock, Rex L Williams, et al.
Cancer Chemotherapy and Pharmacology
|
February 17, 2020
Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors
Anthony W Tolcher, Razelle Kurzrock, Vincente Valero, et al.
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of 1
Search research articles
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Showing results (1-10 of 9) with videos related to
Sort By:
Page
of 1
Clinical Pharmacology in Drug Development
|
November 4, 2022
Population Pharmacokinetics of Oral Migalastat in Adolescents and Adults With and Without Renal Impairment
Cathrine Leonowens, Virginia Schmith, Jie Zhou, et al.
Journal of Clinical Pharmacology
|
January 11, 2014
Population pharmacokinetics of dabrafenib, a BRAF inhibitor: effect of dose, time, covariates, and relationship with its metabolites
Daniele Ouellet, Ekaterina Gibiansky, Cathrine Leonowens, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
November 26, 2024
MDMA pharmacokinetics: A population and physiologically based pharmacokinetics model-informed analysis
Marilyn A Huestis, William B Smith, Cathrine Leonowens, et al.
Cancer Chemotherapy and Pharmacology
|
March 5, 2016
Population pharmacokinetics and exposure-response of trametinib, a MEK inhibitor, in patients with BRAF V600 mutation-positive melanoma
Daniele Ouellet, Nastya Kassir, Joannellyn Chiu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 28, 2019
Indinavir Increases Midazolam <i>N</i>-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach
Dan-Dan Tian, Cathrine Leonowens, Emily J Cox, et al.
British Journal of Clinical Pharmacology
|
March 11, 2014
Concomitant oral and intravenous pharmacokinetics of trametinib, a MEK inhibitor, in subjects with solid tumours
Cathrine Leonowens, Carolyn Pendry, John Bauman, et al.
Journal of Clinical Anesthesia
|
June 26, 2020
Population pharmacokinetic/pharmacodynamic modeling for remimazolam in the induction and maintenance of general anesthesia in healthy subjects and in surgical subjects
Jie Zhou, Cathrine Leonowens, Vijay D Ivaturi, et al.
Cancer Research Communications
|
November 12, 2024
Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma
Todd Shearer, Melissa Comstock, Rex L Williams, et al.
Cancer Chemotherapy and Pharmacology
|
February 17, 2020
Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors
Anthony W Tolcher, Razelle Kurzrock, Vincente Valero, et al.
Page
of 1