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The Biochemical Journal|April 30, 2020
Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitorsChase H Melick, Jenna L Jewell
Genes|August 29, 2020
Regulation of mTORC1 by Upstream StimuliChase H Melick, Jenna L Jewell
The Journal of Biological Chemistry|April 22, 2020
A-kinase anchoring protein 8L interacts with mTORC1 and promotes cell growthChase H Melick, Delong Meng, Jenna L Jewell
Molecular Pharmacology|December 30, 2021
G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 RegulationChase H Melick, Tshering D Lama-Sherpa, Adna Curukovic, et al.
The Journal of Biological Chemistry|February 6, 2020
Glutamine and asparagine activate mTORC1 independently of Rag GTPasesDelong Meng, Qianmei Yang, Huanyu Wang, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|December 30, 2017
Growth Differentiation Factor 6 Promotes Vascular Stability by Restraining Vascular Endothelial Growth Factor SignalingShlomo Krispin, Amber N Stratman, Chase H Melick, et al.
The EMBO Journal|May 14, 2021
ArfGAP1 inhibits mTORC1 lysosomal localization and activationDelong Meng, Qianmei Yang, Chase H Melick, et al.
The EMBO Journal|September 19, 2014
Discrete Notch signaling requirements in the specification of hematopoietic stem cellsAlbert D Kim, Chase H Melick, Wilson K Clements, et al.
Plos Genetics|October 21, 2021
AKAP13 couples GPCR signaling to mTORC1 inhibitionShihai Zhang, Huanyu Wang, Chase H Melick, et al.
Elife|May 22, 2019
GPCR signaling inhibits mTORC1 via PKA phosphorylation of RaptorJenna L Jewell, Vivian Fu, Audrey W Hong, et al.
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