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Nucleic Acids Research|October 14, 2020
dbGuide: a database of functionally validated guide RNAs for genome editing in human and mouse cellsAlexander A Gooden, Christine N Evans, Timothy P Sheets, et al.The Journal of Biological Chemistry|June 24, 2023
An engineered cell line with a hRpn1-attached handle to isolate proteasomesHitendra Negi, Vasty Osei-Amponsa, Bishoy Ibrahim, et al.Molecular and Cellular Biology|July 8, 2020
Impact of Losing hRpn13 Pru or UCHL5 on Proteasome Clearance of Ubiquitinated Proteins and RA190 CytotoxicityVasty Osei-Amponsa, Vinidhra Sridharan, Mayank Tandon, et al.Science Advances|February 14, 2024
Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platformLiping Yang, Timothy P Sheets, Yang Feng, et al.Plos Genetics|September 15, 2023
Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variantsSounak Sahu, Teresa L Sullivan, Alexander Y Mitrophanov, et al.Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer|February 1, 2020
Sensitivity of Mesothelioma Cells to PARP Inhibitors Is Not Dependent on BAP1 but Is Enhanced by Temozolomide in Cells With High-Schlafen 11 and Low-O6-methylguanine-DNA Methyltransferase ExpressionDaniel Rathkey, Manakamana Khanal, Junko Murai, et al.Cancer Immunology Research|July 1, 2021
Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor ResponseBenjamin Ruf, Vanessa V Catania, Simon Wabitsch, et al.Cancer Research|April 10, 2021
Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET ProteinsPoonam Tewary, Alan D Brooks, Ya-Ming Xu, et al.Nature Communications|December 17, 2021
Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myelomaXiuxiu Lu, Venkata R Sabbasani, Vasty Osei-Amponsa, et al.Cell|August 18, 2023
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive marginBenjamin Ruf, Matthias Bruhns, Sepideh Babaei, et al.Pageof 1