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Journal of Molecular and Cellular Cardiology|June 1, 2014
Ranolazine inhibition of hERG potassium channels: drug-pore interactions and reduced potency against inactivation mutantsChunyun Du, Yihong Zhang, Aziza El Harchi, et al.Pharmaceuticals (Basel, Switzerland)|September 28, 2023
Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 AnalogueMatthew V Helliwell, Yihong Zhang, Aziza El Harchi, et al.Journal of Molecular and Cellular Cardiology|October 13, 2011
Molecular determinants of hERG potassium channel inhibition by disopyramideAziza El Harchi, Yi H Zhang, Leyla Hussein, et al.Frontiers in Pharmacology|November 7, 2022
Evolutionary coupling analysis guides identification of mistrafficking-sensitive variants in cardiac K+ channels: Validation with hERGYihong Zhang, Amy L Grimwood, Jules C Hancox, et al.Biophysical Journal|November 25, 2014
Voltage sensor gating charge transfer in a hERG potassium channel modelCharlotte K Colenso, Yang Cao, Richard B Sessions, et al.Journal of Chemical Information and Modeling|January 30, 2014
Assessing hERG pore models as templates for drug docking using published experimental constraints: the inactivated state in the context of drug blockChristopher E Dempsey, Dominic Wright, Charlotte K Colenso, et al.Journal of Electrocardiology|May 25, 2010
Characterization of recombinant hERG K(+) channel inhibition by the active metabolite of amiodarone desethyl-amiodaroneYi H Zhang, Hongwei Cheng, Vadim A Alexeenko, et al.Physiological Reports|March 10, 2020
The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadineAziza El Harchi, Andrew S Butler, Yihong Zhang, et al.The Journal of Physical Chemistry. B|August 27, 2009
Specificity of ion-protein interactions: complementary and competitive effects of tetrapropylammonium, guanidinium, sulfate, and chloride ionsPhilip E Mason, Christopher E Dempsey, Lubos Vrbka, et al.Journal of Chemical Information and Modeling|May 16, 2013
Interactions between voltage sensor and pore domains in a hERG K+ channel model from molecular simulations and the effects of a voltage sensor mutationCharlotte K Colenso, Richard B Sessions, Yi H Zhang, et al.Pageof 5