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Cancers|January 26, 2024
CIC-DUX4 Chromatin Profiling Reveals New Epigenetic Dependencies and Actionable Therapeutic Targets in CIC-Rearranged SarcomasArnaud Bakaric, Luisa Cironi, Viviane Praz, et al.Cell Reports|December 28, 2018
Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple MyelomaMariateresa Fulciniti, Charles Y Lin, Mehmet K Samur, et al.Nature Structural & Molecular Biology|July 24, 2023
Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilitiesYuxiang Zhang, David Remillard, Ugoma Onubogu, et al.Cancer Cell|December 4, 2018
Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic LeukemiaChristopher J Ott, Alexander J Federation, Logan S Schwartz, et al.The Journal of Experimental Medicine|October 7, 2015
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesisAaron D Viny, Christopher J Ott, Barbara Spitzer, et al.RSC Medicinal Chemistry|March 17, 2025
Development of p300-targeting degraders with enhanced selectivity and onset of degradationGraham P Marsh, Mark S Cooper, Sean Goggins, et al.Cell Reports|March 2, 2017
BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1Simon J Hogg, Stephin J Vervoort, Sumit Deswal, et al.Nature Chemical Biology|March 7, 2018
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligandsLara N Gechijian, Dennis L Buckley, Matthew A Lawlor, et al.Cell Stem Cell|September 10, 2019
Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and DifferentiationAaron D Viny, Robert L Bowman, Yu Liu, et al.Cell Chemical Biology|March 28, 2025
Targeted degradation of CDK9 potently disrupts the MYC-regulated networkMohammed A Toure, Keisuke Motoyama, Yichen Xiang, et al.Pageof 6