Showing results (11-20 of 21) with videos related to
Sort By:
Pageof 3
The EMBO Journal|May 24, 2008
pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formationIan J Frew, Claudio R Thoma, Strahil Georgiev, et al.Nature Cell Biology|July 22, 2009
VHL loss causes spindle misorientation and chromosome instabilityClaudio R Thoma, Alberto Toso, Katrin L Gutbrodt, et al.Cell|October 4, 2011
Global identification of modular cullin-RING ligase substratesMichael J Emanuele, Andrew E H Elia, Qikai Xu, et al.Scientific Reports|November 19, 2020
Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screenLina Schukur, Tamara Zimmermann, Ole Niewoehner, et al.ACS Medicinal Chemistry Letters|July 19, 2023
Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation FieldAnna Vulpetti, Philipp Holzer, Niko Schmiedeberg, et al.Neoplasia (New York, N.Y.)|July 19, 2012
Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinomaGunther Boysen, Damaris Bausch-Fluck, Claudio R Thoma, et al.Cell Chemical Biology|September 9, 2021
A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probesBenika J Pinch, Dennis L Buckley, Scott Gleim, et al.Nature|July 13, 2022
Structure of the MRAS-SHOC2-PP1C phosphatase complexZachary J Hauseman, Michelle Fodor, Anxhela Dhembi, et al.Blood Cancer Journal|July 19, 2022
BRD9 degraders as chemosensitizers in acute leukemia and multiple myelomaEllen Weisberg, Basudev Chowdhury, Chengcheng Meng, et al.Nature|May 7, 2025
Targeting the SHOC2-RAS interaction in RAS-mutant cancersZachary J Hauseman, Frédéric Stauffer, Kim S Beyer, et al.Pageof 3