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Journal of Pharmaceutical Sciences|January 1, 2009
The development and validation of a computational model to predict rat liver microsomal clearanceCheng Chang, David B Duignan, Kjell D Johnson, et al.Lab on a Chip|January 15, 2020
Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterizationStephen Fowler, Wen Li Kelly Chen, David B Duignan, et al.Plos One|September 8, 2018
Prodrugs for colon-restricted delivery: Design, synthesis, and in vivo evaluation of colony stimulating factor 1 receptor (CSF1R) inhibitorsDawn M George, Raymond J Huntley, Kevin Cusack, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|February 19, 2009
Role of hepatic transporters in the disposition and hepatotoxicity of a HER2 tyrosine kinase inhibitor CP-724,714Bo Feng, Jinghai J Xu, Yi-An Bi, et al.Journal of Medicinal Chemistry|September 26, 2014
Optimized protein kinase Cθ (PKCθ) inhibitors reveal only modest anti-inflammatory efficacy in a rodent model of arthritisDawn M George, Eric C Breinlinger, Maria A Argiriadi, et al.Journal of Medicinal Chemistry|July 8, 2014
Discovery of selective and orally bioavailable protein kinase Cθ (PKCθ) inhibitors from a fragment hitDawn M George, Eric C Breinlinger, Michael Friedman, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 10, 2007
Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and humanAmit S Kalgutkar, Bo Feng, Hang T Nguyen, et al.Experimental Biology and Medicine (Maywood, N.J.)|June 18, 2017
Navigating tissue chips from development to dissemination: A pharmaceutical industry perspectiveLorna Ewart, Kristin Fabre, Ananthsrinivas Chakilam, et al.Current Drug Metabolism|November 11, 2008
High throughput ADME screening: practical considerations, impact on the portfolio and enabler of in silico ADME modelsCornelis E C A Hop, Mark J Cole, Ralph E Davidson, et al.Journal of Medicinal Chemistry|July 9, 2025
Discovery of Orally Efficacious Bridged Piperazines as smTNF ModulatorsZhiguo Bian, Robert G Schmidt, Noel S Wilson, et al.Pageof 3