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ACS Medicinal Chemistry Letters|November 20, 2024
Cyclic Peptide C5aR1 Antagonist Design Using Solution Conformational Analysis Derived from Residual Dipolar CouplingsKathleen A Farley, Ye Che, Ricardo Lira, et al.Cell Chemical Biology|October 18, 2016
A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein TranslationDonna N Petersen, Julie Hawkins, Wanida Ruangsiriluk, et al.Journal of Immunology (Baltimore, Md. : 1950)|August 14, 2016
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary InflammationMichael J Primiano, Bruce A Lefker, Michael R Bowman, et al.European Journal of Medicinal Chemistry|January 20, 2018
Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitorsFrank Lovering, Paul Morgan, Christophe Allais, et al.Journal of Computer-Aided Molecular Design|May 24, 2011
Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metricsWan F Lau, Jane M Withka, David Hepworth, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case ExampleMarkus Boehm, David Hepworth, Paula M Loria, et al.ACS Medicinal Chemistry Letters|February 21, 2015
Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonistsSuvi T M Orr, Ramsay Beveridge, Samit K Bhattacharya, et al.Journal of Medicinal Chemistry|April 18, 2014
Identification of (R)-6-(1-(4-cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic acid, a highly potent and selective nonsteroidal mineralocorticoid receptor antagonistAgustin Casimiro-Garcia, David W Piotrowski, Catherine Ambler, et al.Journal of Medicinal Chemistry|August 11, 2015
Discovery of Selective Small Molecule Inhibitors of Monoacylglycerol Acyltransferase 3Kim Huard, Allyn T Londregan, Gregory Tesz, et al.Molecular Systems Biology|May 12, 2025
Data- and knowledge-derived functional landscape of human solute carriersUlrich Goldmann, Tabea Wiedmer, Andrea Garofoli, et al.Pageof 5