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Molecular Biology of the Cell|March 30, 2004
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblastsXu Shi-Wen, Yunliang Chen, Christopher P Denton, et al.The American Journal of Pathology|November 30, 2005
Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic diseaseYunliang Chen, Xu Shi-Wen, Jonathan van Beek, et al.Journal of Immunology (Baltimore, Md. : 1950)|April 5, 2015
Macrophage epoxygenase determines a profibrotic transcriptome signatureJacques Behmoaras, Ana Garcia Diaz, Lara Venda, et al.Arthritis & Rheumatology (Hoboken, N.J.)|January 13, 2025
Critical Role for Transglutaminase 2 in Scleroderma Skin Fibrosis and in the Development of Dermal Sclerosis in a Mouse Model of SclerodermaAngela Y Y Tam, Korsa Khan, Shiwen Xu, et al.Clinical Science (London, England : 1979)|January 9, 2016
Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosisIona C Evans, Josephine L Barnes, Ian M Garner, et al.The Journal of Biological Chemistry|March 27, 2004
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERKShi-wen Xu, Sarah L Howat, Elisabetta A Renzoni, et al.Arthritis and Rheumatism|July 1, 2009
Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagenMarkella Ponticos, Alan M Holmes, Xu Shi-wen, et al.Arthritis Research & Therapy|July 6, 2017
Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signatureEmma C Derrett-Smith, Viktor Martyanov, Cecilia B Chighizola, et al.Matrix Biology : Journal of the International Society for Matrix Biology|August 8, 2007
Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblastsXu Shi-Wen, Elisabetta A Renzoni, Laura Kennedy, et al.Arthritis and Rheumatism|February 2, 2008
Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblastsYunliang Chen, Andrew Leask, David J Abraham, et al.Pageof 12