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Expert Opinion on Therapeutic Patents
|
February 26, 2010
Novel CCR5 antagonists for the treatment of HIV infection: a review of compounds patented in 2006 - 2008
Hanbiao Yang, David M Rotstein
Bioorganic & Medicinal Chemistry Letters
|
July 21, 2010
Exploration of a new series of CCR5 antagonists: multi-dimensional optimization of a sub-series containing N-substituted pyrazoles
Rémy C Lemoine, Ann C Petersen, Lina Setti, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 19, 2008
Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist
Hanbiao Yang, Xiao-Fa Lin, Fernando Padilla, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 22, 2010
Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle series
Jutta Wanner, Lijing Chen, Rémy C Lemoine, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 9, 2010
Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc
Rémy C Lemoine, Ann C Petersen, Lina Setti, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 24, 2010
Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists
Rémy C Lemoine, Ann C Petersen, Lina Setti, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 12, 2010
Synthesis, SAR and evaluation of [1,4']-bipiperidinyl-4-yl-imidazolidin-2-one derivatives as novel CCR5 antagonists
David M Rotstein, Stephen D Gabriel, Nicole Manser, et al.
British Journal of Pharmacology
|
March 18, 2014
A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands
David C Swinney, Paul Beavis, Kai-Ting Chuang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 14, 2009
Spiropiperidine CCR5 antagonists
David M Rotstein, Stephen D Gabriel, Ferenc Makra, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 27, 2010
Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists
David M Rotstein, Chris R Melville, Fernando Padilla, et al.
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of 1
Search research articles
Search
Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
Expert Opinion on Therapeutic Patents
|
February 26, 2010
Novel CCR5 antagonists for the treatment of HIV infection: a review of compounds patented in 2006 - 2008
Hanbiao Yang, David M Rotstein
Bioorganic & Medicinal Chemistry Letters
|
July 21, 2010
Exploration of a new series of CCR5 antagonists: multi-dimensional optimization of a sub-series containing N-substituted pyrazoles
Rémy C Lemoine, Ann C Petersen, Lina Setti, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 19, 2008
Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist
Hanbiao Yang, Xiao-Fa Lin, Fernando Padilla, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 22, 2010
Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle series
Jutta Wanner, Lijing Chen, Rémy C Lemoine, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 9, 2010
Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc
Rémy C Lemoine, Ann C Petersen, Lina Setti, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 24, 2010
Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists
Rémy C Lemoine, Ann C Petersen, Lina Setti, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 12, 2010
Synthesis, SAR and evaluation of [1,4']-bipiperidinyl-4-yl-imidazolidin-2-one derivatives as novel CCR5 antagonists
David M Rotstein, Stephen D Gabriel, Nicole Manser, et al.
British Journal of Pharmacology
|
March 18, 2014
A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands
David C Swinney, Paul Beavis, Kai-Ting Chuang, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 14, 2009
Spiropiperidine CCR5 antagonists
David M Rotstein, Stephen D Gabriel, Ferenc Makra, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 27, 2010
Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists
David M Rotstein, Chris R Melville, Fernando Padilla, et al.
Page
of 1