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Expert Opinion on Drug Discovery
|
June 1, 2012
Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk
David R Janero, Loren Lindsley, Venkata Kiran Vemuri, et al.
Methods in Enzymology
|
July 29, 2017
Design and Synthesis of Cannabinoid 1 Receptor (CB1R) Allosteric Modulators: Drug Discovery Applications
Abhijit R Kulkarni, Sumanta Garai, David R Janero, et al.
Bioorganic & Medicinal Chemistry
|
October 16, 2020
Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility
Peter C Schaffer, Pushkar M Kulkarni, David R Janero, et al.
Current Topics in Medicinal Chemistry
|
February 20, 2007
Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers
Subhash P Khanapure, David S Garvey, David R Janero, et al.
Molecular Biosystems
|
May 14, 2010
Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacological inhibition, and catalytic mechanism
Ioannis Karageorgos, Sergiy Tyukhtenko, Nikolai Zvonok, et al.
Methodist Debakey Cardiovascular Journal
|
November 10, 2016
Nucleic Acid Delivery for Endothelial Dysfunction in Cardiovascular Diseases
Dipti Deshpande, David R Janero, Victor Segura-Ibarra, et al.
Biochemical and Biophysical Research Communications
|
April 29, 2009
Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments
Elvis K Tiburu, Sergiy Tyukhtenko, Lalit Deshmukh, et al.
Biochemical and Biophysical Research Communications
|
September 22, 2009
NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation
Sergiy Tyukhtenko, Elvis K Tiburu, Lalit Deshmukh, et al.
Chemistry & Biology
|
November 2, 2010
hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation
Richard W Mercier, Ying Pei, Lakshmipathi Pandarinathan, et al.
The AAPS Journal
|
January 15, 2011
Human cannabinoid 1 GPCR C-terminal domain interacts with bilayer phospholipids to modulate the structure of its membrane environment
Elvis K Tiburu, Sergiy Tyukhtenko, Han Zhou, et al.
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Search research articles
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Showing results (21-30 of 69) with videos related to
Sort By:
Page
of 7
Expert Opinion on Drug Discovery
|
June 1, 2012
Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk
David R Janero, Loren Lindsley, Venkata Kiran Vemuri, et al.
Methods in Enzymology
|
July 29, 2017
Design and Synthesis of Cannabinoid 1 Receptor (CB1R) Allosteric Modulators: Drug Discovery Applications
Abhijit R Kulkarni, Sumanta Garai, David R Janero, et al.
Bioorganic & Medicinal Chemistry
|
October 16, 2020
Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility
Peter C Schaffer, Pushkar M Kulkarni, David R Janero, et al.
Current Topics in Medicinal Chemistry
|
February 20, 2007
Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers
Subhash P Khanapure, David S Garvey, David R Janero, et al.
Molecular Biosystems
|
May 14, 2010
Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacological inhibition, and catalytic mechanism
Ioannis Karageorgos, Sergiy Tyukhtenko, Nikolai Zvonok, et al.
Methodist Debakey Cardiovascular Journal
|
November 10, 2016
Nucleic Acid Delivery for Endothelial Dysfunction in Cardiovascular Diseases
Dipti Deshpande, David R Janero, Victor Segura-Ibarra, et al.
Biochemical and Biophysical Research Communications
|
April 29, 2009
Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments
Elvis K Tiburu, Sergiy Tyukhtenko, Lalit Deshmukh, et al.
Biochemical and Biophysical Research Communications
|
September 22, 2009
NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation
Sergiy Tyukhtenko, Elvis K Tiburu, Lalit Deshmukh, et al.
Chemistry & Biology
|
November 2, 2010
hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation
Richard W Mercier, Ying Pei, Lakshmipathi Pandarinathan, et al.
The AAPS Journal
|
January 15, 2011
Human cannabinoid 1 GPCR C-terminal domain interacts with bilayer phospholipids to modulate the structure of its membrane environment
Elvis K Tiburu, Sergiy Tyukhtenko, Han Zhou, et al.
Page
of 7