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Molecular Brain|May 6, 2020
Axl receptor tyrosine kinase is a regulator of apolipoprotein EWenchen Zhao, Jianjia Fan, Iva Kulic, et al.Journal of Medicinal Chemistry|January 14, 2014
Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognitionDean G Brown, Peter R Bernstein, Andrew Griffin, et al.ACS Chemical Biology|October 17, 2024
Novel Corrector for Variants of SLC6A8: A Therapeutic Opportunity for Creatine Transporter DeficiencyLara N Gechijian, Giovanni Muncipinto, T Justin Rettenmaier, et al.Journal of Medicinal Chemistry|June 5, 2007
Pyridazinoquinolinetriones as NMDA glycine-site antagonists with oral antinociceptive activity in a model of neuropathic painThomas M Bare, Dean G Brown, Carey L Horchler, et al.JCI Insight|November 8, 2024
SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanineHeike J Wobst, Andreu Viader, Giovanni Muncipinto, et al.Bioorganic & Medicinal Chemistry Letters|August 24, 2010
Discovery of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as selective antagonists of the kappa opioid receptor. Part 1Todd A Brugel, Reed W Smith, Michael Balestra, et al.SLAS Discovery : Advancing Life Sciences R & D|January 10, 2018
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the TargetDean G Brown, Giles A Brown, Paolo Centrella, et al.Nature|April 27, 2017
Structural insight into allosteric modulation of protease-activated receptor 2Robert K Y Cheng, Cédric Fiez-Vandal, Oliver Schlenker, et al.Bioorganic & Medicinal Chemistry Letters|November 12, 2010
4-aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulatorsHui Xiong, Todd A Brugel, Michael Balestra, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activityDean G Brown, Peter R Bernstein, Ye Wu, et al.Pageof 6