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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|May 26, 2026
A first-in-pediatric study of ALRN-6924, a novel stapled-peptide dual MDM2/MDMX inhibitor, for children with advanced hematologic and solid malignanciesDavid S Shulman, Kieuhoa T Vo, Frank M Balis, et al.
The Journal of Experimental Medicine|March 23, 2023
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapyChong Zuo, John M Baer, Brett L Knolhoff, et al.
Science Immunology|August 15, 2025
Combined Flt3L and CD40 agonism restores dendritic cell-driven T cell immunity in pancreatic cancerGraham D Hogg, Alyssa G Weinstein, Natalie L Kingston, et al.
Cancer Discovery|March 8, 2023
p38MAPKα Stromal Reprogramming Sensitizes Metastatic Breast Cancer to ImmunotherapyDouglas V Faget, Xianmin Luo, Matthew J Inkman, et al.
Neuron|March 12, 2026
Brain-engrafted monocyte-derived macrophages from blood and skull-bone marrow exhibit distinct propertiesSiling Du, Feiya Ou, Antoine Drieu, et al.
Neurosurgery|February 21, 2020
The Hydrogel Endovascular Aneurysm Treatment Trial (HEAT): A Randomized Controlled Trial of the Second-Generation Hydrogel CoilBernard R Bendok, Karl R Abi-Aad, Jennifer D Ward, et al.
The Journal of Clinical Investigation|September 14, 2021
Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironmentXinming Su, Yalin Xu, Gregory C Fox, et al.
Cancer Research|May 25, 2016
Antagonizing Integrin β3 Increases Immunosuppression in CancerXinming Su, Alison K Esser, Sarah R Amend, et al.
Nature Communications|March 21, 2024
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancerAshenafi Bulle, Peng Liu, Kuljeet Seehra, et al.
Science Immunology|June 26, 2026
Treg cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I-deficient metastatic pancreatic cancerZoe C Schmiechen, Eduardo Cruz-Hinojoza, Audrey L Hilk, et al.
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