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Cold Spring Harbor Perspectives in Medicine|December 3, 2016
The Evolution of the Ribosomal Protein-MDM2-p53 PathwayChad Deisenroth, Derek A Franklin, Yanping ZhangCancer Research|December 6, 2014
MDM2-p53 pathway in hepatocellular carcinomaXuan Meng, Derek A Franklin, Jiahong Dong, et al.Cell Reports|August 9, 2018
p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback LoopPatrick L Leslie, Derek A Franklin, Yong Liu, et al.Cell Reports|January 26, 2017
Protection against High-Fat-Diet-Induced Obesity in MDM2C305F Mice Due to Reduced p53 Activity and Enhanced Energy ExpenditureShijie Liu, Tae-Hyung Kim, Derek A Franklin, et al.Cancer Drug Resistance (Alhambra, Calif.)|October 16, 2020
MEK inhibition activates STAT signaling to increase breast cancer immunogenicity via MHC-I expressionDerek A Franklin, Jamaal L James, Margaret L Axelrod, et al.Oncotarget|October 15, 2017
p53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2BJiehui Di, Juanjuan Tang, Heya Qian, et al.Scientific Reports|December 1, 2016
p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathwayDerek A Franklin, Yizhou He, Patrick L Leslie, et al.Journal of Medicinal Chemistry|May 3, 2011
Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphate δ-ester modifications as selective agonists of the P2Y(4) receptorHiroshi Maruoka, M P Suresh Jayasekara, Matthew O Barrett, et al.The Journal of Biological Chemistry|November 26, 2022
Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathwayDerek A Franklin, Shijie Liu, Aiwen Jin, et al.JCI Insight|July 8, 2020
MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBCDerek A Franklin, Joe T Sharick, Paula I Ericsson-Gonzalez, et al.Pageof 1