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Immunological Reviews|August 10, 2020
Therapeutic modulation of inflammasome pathwaysDhruv Chauhan, Lieselotte Vande Walle, Mohamed Lamkanfi
The Journal of Biological Chemistry|November 11, 2015
A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome ActivationJonathan L Schmid-Burgk, Dhruv Chauhan, Tobias Schmidt, et al.
Viruses|November 11, 2022
In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral TherapeuticsDhruv Chauhan, Nikhil Chakravarty, Arjit Vijey Jeyachandran, et al.
ACS Chemical Biology|September 6, 2018
Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutumFrank Surup, Dhruv Chauhan, Jutta Niggemann, et al.
The EMBO Journal|November 27, 2014
Cytosolic RNA:DNA hybrids activate the cGAS-STING axisArun K Mankan, Tobias Schmidt, Dhruv Chauhan, et al.
Immunity|April 3, 2016
Human Monocytes Engage an Alternative Inflammasome PathwayMoritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, et al.
Cell Reports|November 29, 2018
BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in MacrophagesDhruv Chauhan, Eva Bartok, Moritz M Gaidt, et al.
Cell|October 17, 2017
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, et al.
EMBO Reports|July 28, 2022
GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosisDhruv Chauhan, Dieter Demon, Lieselotte Vande Walle, et al.
Nature Communications|February 7, 2024
Structural basis for the oligomerization-facilitated NLRP3 activationXiaodi Yu, Rosalie E Matico, Robyn Miller, et al.
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